Viral meningitis laboratory findings: Difference between revisions
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Samples can be taken by different ways from the suspected meningitis patients.They may be collected for testing by:<ref name= "Viral meningitis"> CDC https://www.cdc.gov/meningitis/viral.html Accessed on April 20, 2017 </ref> | Samples can be taken by different ways from the suspected meningitis patients to detect the virus causing the disease.They may be collected for testing by:<ref name= "Viral meningitis"> CDC https://www.cdc.gov/meningitis/viral.html Accessed on April 20, 2017 </ref> | ||
*Nose swabbing | *Nose swabbing | ||
*Throat swabbing | *Throat swabbing | ||
Revision as of 21:05, 20 April 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Laboratory findings
Non specific tests
Blood tests
It is performed routinely to any suspected meningitis patients. It includes the following:
- CBC
- Blood culture
- PT and PTT
- Glucose level
- Creatine level
Different tissue samples
Samples can be taken by different ways from the suspected meningitis patients to detect the virus causing the disease.They may be collected for testing by:[1]
- Nose swabbing
- Throat swabbing
- Rectum swabbing
- Taking a stool sample
- Drawing fluid from around your spinal cord.
Specific tests
Specific diagnostic tests include lumbar puncture with CSF examination. CSF examination findings in viral meningitis are as follows:
| Cerebrospinal fluid level | Normal level | Viral meningitis[2] |
|---|---|---|
| Cells/ul | < 5 | >100 |
| Cells | Lymphos:Monos 7:3 | Lymphocytes>granulocytes |
| Total protein (mg/dl) | 45-60 | Normal or slightly elevated |
| Glucose ratio (CSF/plasma)[3] | > 0.5 | >0.6 |
| Lactate (mmols/l)[4] | < 2.1 | < 2.1 |
| Others | ICP:6-12 (cm H2O) | Throat swap |
References
- ↑ CDC https://www.cdc.gov/meningitis/viral.html Accessed on April 20, 2017
- ↑ Negrini B, Kelleher KJ, Wald ER (2000). "Cerebrospinal fluid findings in aseptic versus bacterial meningitis". Pediatrics. 105 (2): 316–9. PMID 10654948.
- ↑ Chow E, Troy SB (2014). "The differential diagnosis of hypoglycorrhachia in adult patients". Am J Med Sci. 348 (3): 186–90. doi:10.1097/MAJ.0000000000000217. PMC 4065645. PMID 24326618.
- ↑ Leen WG, Willemsen MA, Wevers RA, Verbeek MM (2012). "Cerebrospinal fluid glucose and lactate: age-specific reference values and implications for clinical practice". PLoS One. 7 (8): e42745. doi:10.1371/journal.pone.0042745. PMC 3412827. PMID 22880096.