Candida vulvovaginitis classification: Difference between revisions

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==Classification==
==Classification==
[[Candida]] [[vulvovaginitis]] can be classified based on the duration of the infection and based on the [[strain]] of [[Candida]] causing the infection. 
===Duration===
[[Candida]] [[vulvovaginitis]] can be divided based on the duration and number of episodes of the infection into:<ref name="pmid16990387">{{cite journal |vauthors=Eckert LO |title=Clinical practice. Acute vulvovaginitis |journal=N. Engl. J. Med. |volume=355 |issue=12 |pages=1244–52 |year=2006 |pmid=16990387 |doi=10.1056/NEJMcp053720 |url=}}</ref><ref name="pmid9500475">{{cite journal |vauthors=Sobel JD, Faro S, Force RW, Foxman B, Ledger WJ, Nyirjesy PR, Reed BD, Summers PR |title=Vulvovaginal candidiasis: epidemiologic, diagnostic, and therapeutic considerations |journal=Am. J. Obstet. Gynecol. |volume=178 |issue=2 |pages=203–11 |year=1998 |pmid=9500475 |doi= |url=}}</ref><ref name="pmid17560449">{{cite journal |vauthors=Sobel JD |title=Vulvovaginal candidosis |journal=Lancet |volume=369 |issue=9577 |pages=1961–71 |year=2007 |pmid=17560449 |doi=10.1016/S0140-6736(07)60917-9 |url=}}</ref><ref name="pmid7995997">{{cite journal |vauthors=Vazquez JA, Sobel JD, Demitriou R, Vaishampayan J, Lynch M, Zervos MJ |title=Karyotyping of Candida albicans isolates obtained longitudinally in women with recurrent vulvovaginal candidiasis |journal=J. Infect. Dis. |volume=170 |issue=6 |pages=1566–9 |year=1994 |pmid=7995997 |doi= |url=}}</ref>
*'''Acute, uncomplicated''': these are usually sporadic cases of [[Candida]] [[vulvovaginitis]], which respond to [[topical]] [[antifungal therapy]] and have a high cure rate.
*'''Acute, complicated''': symptoms are more severe than uncomplicated infections and typically require a combination of oral and topical [[anti-fungal]] treatment.
*'''Recurrent Vulvovaginal Candidiasis (RVVC)''': defined as 4 or more episodes of [[Candida]] [[vulvovaginitis]] per year, usually caused by the same [[strain]] of [[Candida]]. Treatment also requires a combination of oral and [[topical]] [[antifungal agents]].
*According to 2015, Treatment of STD guidelines - Candida vulvovaginitis can be classified into uncomplicated and complicated based on the following features:<ref name="pmid26602614">{{cite journal| author=Workowski KA| title=Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines. | journal=Clin Infect Dis | year= 2015 | volume= 61 Suppl 8 | issue=  | pages= S759-62 | pmid=26602614 | doi=10.1093/cid/civ771 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26602614  }}</ref>


===Candida Vulvovaginitis===
{| class="wikitable"
[[Candida]] [[vulvovaginitis]] can be classified based on the duration, as well as the strain of [[Candida]] causing the infection. 
!Uncomplicated Candida Vulvovaginitis  
 
!Complicated Candida Vulvovaginitis
====Duration====
|-
[[Candida]] [[vulvovaginitis]] can be divided based on the duration of the infection into:<ref name="pmid16990387">{{cite journal |vauthors=Eckert LO |title=Clinical practice. Acute vulvovaginitis |journal=N. Engl. J. Med. |volume=355 |issue=12 |pages=1244–52 |year=2006 |pmid=16990387 |doi=10.1056/NEJMcp053720 |url=}}</ref><ref name="pmid9500475">{{cite journal |vauthors=Sobel JD, Faro S, Force RW, Foxman B, Ledger WJ, Nyirjesy PR, Reed BD, Summers PR |title=Vulvovaginal candidiasis: epidemiologic, diagnostic, and therapeutic considerations |journal=Am. J. Obstet. Gynecol. |volume=178 |issue=2 |pages=203–11 |year=1998 |pmid=9500475 |doi= |url=}}</ref><ref name="pmid17560449">{{cite journal |vauthors=Sobel JD |title=Vulvovaginal candidosis |journal=Lancet |volume=369 |issue=9577 |pages=1961–71 |year=2007 |pmid=17560449 |doi=10.1016/S0140-6736(07)60917-9 |url=}}</ref><ref name="pmid7995997">{{cite journal |vauthors=Vazquez JA, Sobel JD, Demitriou R, Vaishampayan J, Lynch M, Zervos MJ |title=Karyotyping of Candida albicans isolates obtained longitudinally in women with recurrent vulvovaginal candidiasis |journal=J. Infect. Dis. |volume=170 |issue=6 |pages=1566–9 |year=1994 |pmid=7995997 |doi= |url=}}</ref>
|
*Acute, uncomplicated: these are usually sporadic cases of [[Candida]] [[vulvovaginitis]], which respond to topical anti-fungal therapy and have a high cure rate
*Sporadic or infrequent VVC 
*Acute, complicated: symptoms are more severe than uncomplicated infections and typically require a combination of oral and topical anti-fungal treatment
*Mild-to-moderate VVC 
*Recurrent: defined as 4 or more cases of [[Candida]] [[vulvovaginitis]] per year, usually caused by the same strain of [[Candida]]. Treatment also requires a combination of oral and topical anti-fungal agents
*Likely to be [[Candida albicans]]  
 
*Non-immunocompromised women
====Microbiology====
|
[[Candida]] [[vulvovaginitis]] can also be divided based on the strain of [[Candida]] causing the infection:<ref name="pmid17560449">{{cite journal |vauthors=Sobel JD |title=Vulvovaginal candidosis |journal=Lancet |volume=369 |issue=9577 |pages=1961–71 |year=2007 |pmid=17560449 |doi=10.1016/S0140-6736(07)60917-9 |url=}}</ref><ref name="pmid15709796">{{cite journal |vauthors=Buscemi L, Arechavala A, Negroni R |title=[Study of acute vulvovaginitis in sexually active adult women, with special reference to candidosis, in patients of the Francisco J. Muñiz Infectious Diseases Hospital] |journal=Rev Iberoam Micol |volume=21 |issue=4 |pages=177–81 |year=2004 |pmid=15709796 |doi= |url=}}</ref><ref name="pmid12932875">{{cite journal |vauthors=Corsello S, Spinillo A, Osnengo G, Penna C, Guaschino S, Beltrame A, Blasi N, Festa A |title=An epidemiological survey of vulvovaginal candidiasis in Italy |journal=Eur. J. Obstet. Gynecol. Reprod. Biol. |volume=110 |issue=1 |pages=66–72 |year=2003 |pmid=12932875 |doi= |url=}}</ref>
*Recurrent VVC 
*''[[C. albicans]]'': comprises the majority of cases of [[Candida]] [[vulvovaginitis]]
*Severe VVC 
*''C. glabrata'': it is the second most common causative pathogen
*Non-albicans candidiasis   
*''C. tropicalis''
*Women with [[diabetes]], [[immunocompromised]] conditions such as [[HIV]] infection), [[debilitation]]
*''C. krusei''
*[[immunosuppressive|Immunosuppressive therapy]]: [[corticosteroids]] use
*''C. parapsilosis''
|}


==References==
==References==

Revision as of 14:08, 1 May 2017

Candidiasis Main page

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Pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Overview

Candida vulvovaginitis can be classified based on the duration, as well as the strain of Candida causing the infection.

Classification

Candida vulvovaginitis can be classified based on the duration of the infection and based on the strain of Candida causing the infection.

Duration

Candida vulvovaginitis can be divided based on the duration and number of episodes of the infection into:[1][2][3][4]

  • Acute, uncomplicated: these are usually sporadic cases of Candida vulvovaginitis, which respond to topical antifungal therapy and have a high cure rate.
  • Acute, complicated: symptoms are more severe than uncomplicated infections and typically require a combination of oral and topical anti-fungal treatment.
  • Recurrent Vulvovaginal Candidiasis (RVVC): defined as 4 or more episodes of Candida vulvovaginitis per year, usually caused by the same strain of Candida. Treatment also requires a combination of oral and topical antifungal agents.
  • According to 2015, Treatment of STD guidelines - Candida vulvovaginitis can be classified into uncomplicated and complicated based on the following features:[5]
Uncomplicated Candida Vulvovaginitis Complicated Candida Vulvovaginitis
  • Sporadic or infrequent VVC
  • Mild-to-moderate VVC
  • Likely to be Candida albicans
  • Non-immunocompromised women

References

  1. Eckert LO (2006). "Clinical practice. Acute vulvovaginitis". N. Engl. J. Med. 355 (12): 1244–52. doi:10.1056/NEJMcp053720. PMID 16990387.
  2. Sobel JD, Faro S, Force RW, Foxman B, Ledger WJ, Nyirjesy PR, Reed BD, Summers PR (1998). "Vulvovaginal candidiasis: epidemiologic, diagnostic, and therapeutic considerations". Am. J. Obstet. Gynecol. 178 (2): 203–11. PMID 9500475.
  3. Sobel JD (2007). "Vulvovaginal candidosis". Lancet. 369 (9577): 1961–71. doi:10.1016/S0140-6736(07)60917-9. PMID 17560449.
  4. Vazquez JA, Sobel JD, Demitriou R, Vaishampayan J, Lynch M, Zervos MJ (1994). "Karyotyping of Candida albicans isolates obtained longitudinally in women with recurrent vulvovaginal candidiasis". J. Infect. Dis. 170 (6): 1566–9. PMID 7995997.
  5. Workowski KA (2015). "Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines". Clin Infect Dis. 61 Suppl 8: S759–62. doi:10.1093/cid/civ771. PMID 26602614.

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