Rotavirus infection laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Laboratory Findings

Specific diagnosis of the disease is made by identification of the virus in the patient's stool. The most widely used diagnostic laboratory method is antigen detection in the stool by an enzyme immunoassay (EIA) directed at an antigen common to all group A rotaviruses (i.e., those that are the principal cause of human disease). Other diagnostic techniques that can be used:

• Electron microscopy
• RNA electrophoresis
• Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR)
• Tissue culture