Ulcerative colitis pathophysiology: Difference between revisions
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*Ulcerative colitis is characterized by inflammation of the mucosa which is diffuse and primarily confined to the colon. | *Ulcerative colitis is characterized by inflammation of the mucosa which is diffuse and primarily confined to the colon. | ||
*The disease can extend proximally in a continuous, circular and uniform manner. | *The disease can extend proximally in a continuous, circular and uniform manner. | ||
*Various factors influencing the pathogenesis of ulcerative colitis include: | |||
**Intestinal Micro bacteria | |||
**Genetics | |||
**Immunological abnormalities | |||
**Environmental factors | |||
===Pathogenesis=== | ===Pathogenesis=== | ||
Revision as of 23:18, 21 May 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
- Ulcerative colitis is characterized by inflammation of the mucosa which is diffuse and primarily confined to the colon.
- The disease can extend proximally in a continuous, circular and uniform manner.
- Various factors influencing the pathogenesis of ulcerative colitis include:
- Intestinal Micro bacteria
- Genetics
- Immunological abnormalities
- Environmental factors
Pathogenesis
The pathogenesis of ulcerative colitis includes:[1]
- Dysregulation of cytokine function
References
- ↑ Guan Q, Zhang J (2017). "Recent Advances: The Imbalance of Cytokines in the Pathogenesis of Inflammatory Bowel Disease". Mediators Inflamm. 2017: 4810258. doi:10.1155/2017/4810258. PMC 5379128. PMID 28420941.