Roseola pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Pathophysiology

Pathogenesis

• The human herpes virus infects the T cells, monocytes-macrophages, epithelial cells, and central nervous system cells resulting in a chronic infection.
• The pathogenicity of HHV-7 is not well understood.

Genetics

• Chromosomal integration of HHV-6A and HHV-6B is responsible for transmission of infection from the parents to the newboen and is observed in 1% of the population.