Roseola classification: Difference between revisions

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Revision as of 19:07, 23 May 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Roseola is classified according to International Committee of Taxonomy on Viruses (ICTV) into two subtypes based on the causative virus:
- HHV6A
- HHV6B

	Classification	Clinical manifestations
Subfamily alphavirinae	Herpes simplex type 1	Perioral vesicular rash Rarely encephalitis Meningitis
Subfamily alphavirinae	Herpes simplex type 2 varicella-zoster virus	Disseminated vesicular rash at acquisition (chicken pox) Localized vesicular rash with reactivation(zoster)
Subfamily betavirinae	Cytomegalovirus	Mononucleosis like illness in healthy adults Fever Pneumonia Hepatitis in immunocompromised adults
	Human herpes virus 6	Acute febrile illness sometimes with rash (roseola infantum)
	Human herpes virus 7	May cause febrile illness sometimes with rash ( roseola-like)
Subfamily gammavirinae	Epstein-Bar virus	mononucleosis, lymphoma, nasopahryngeal carcinoma and hodgkins disease.
Subfamily gammavirinae	Human herpes virus 8	Kaposi's sarcoma in immunocompromised.

↑ Salahuddin SZ, Ablashi DV, Markham PD, Josephs SF, Sturzenegger S, Kaplan M; et al. (1986). "Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders". Science. 234 (4776): 596–601. PMID 2876520.

@@ Line 22: / Line 22: @@
 alphavirinae
 |Herpes simplex type 1
-|Vesicular rash, perioral, rarely encephalitis, meningitis.
+|
+*Perioral vesicular rash
+*Rarely encephalitis
+*Meningitis
 |-
 |Herpes simplex type 2
 varicella-zoster virus
-|Disseminated vesicular rash at acquisition (chicken pox): localized vesicular rash with reactivation(zoster).
+|
+*Disseminated vesicular rash at acquisition (chicken pox)
+*Localized vesicular rash with reactivation(zoster)
 |-
 | rowspan="3" |Subfamily betavirinae
 |Cytomegalovirus
-|Mononucleosi-like illness in healthy adults;
+|
-Fever,
+*Mononucleosis like illness in healthy adults
+Fever
-pneumonia, and
+*Pneumonia
+*Hepatitis in immunocompromised adults
-Hepatitis in immunocompromised adults.
 |-
 |Human herpes virus 6
-|Acute febrile illness sometimes with rash (roseola infantum),
+|Acute febrile illness sometimes with rash (roseola infantum)
 |-
 |Human herpes virus 7
-|May cause febrile illness sometimes with rash ( roseola-like).
+|May cause febrile illness sometimes with rash ( roseola-like)
 |-
 | rowspan="2" |Subfamily