Esophageal candidiasis medical therapy: Difference between revisions
Ahmed Younes (talk | contribs) No edit summary |
Ahmed Younes (talk | contribs) |
||
| Line 5: | Line 5: | ||
==Medical therapy== | ==Medical therapy== | ||
*Esophageal candidiasis is almost always treated with systemic antifungals (either parentral or oral) | |||
*A diagnostic trial of antifungal therapy is tried before performing endoscopy in HIV patients (because candida esophagitis is the most common cause of infectious esophagitis). If no improvement within 5-7 days, then endoscopy is indicated. | |||
===First line antifungal therapy:=== | |||
Oral fluconazole: 200-400 mg * 14-21 | |||
IV fluconazole: 400 mg daily (6mg/kg/day) | |||
AmB-d: 0.3-0.7 mg/day | |||
===In fluconazole refractory patients:=== | |||
Itraconazole: 200 mg daily | |||
Voriconazole: 200 mg twice daily for 14-21 days | |||
Micafungin: 150 mg daily | |||
Caspofungin: 50 mg daily | |||
Anidu-lafungin: 200 mg daily | |||
AmB-d: 0.3 - 0.7 mg/kg daily | |||
===Prophylactic (suppressive) therapy:=== | |||
Fluconazole 100-200 3 times/ week | |||
===HIV patients:=== | |||
HAART therapy decreases recurrence of candida esophagitis. | |||
==References== | ==References== | ||
Revision as of 14:21, 31 May 2017
|
Esophageal candidiasis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Esophageal candidiasis medical therapy On the Web |
|
American Roentgen Ray Society Images of Esophageal candidiasis medical therapy |
|
Risk calculators and risk factors for Esophageal candidiasis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Medical therapy
- Esophageal candidiasis is almost always treated with systemic antifungals (either parentral or oral)
- A diagnostic trial of antifungal therapy is tried before performing endoscopy in HIV patients (because candida esophagitis is the most common cause of infectious esophagitis). If no improvement within 5-7 days, then endoscopy is indicated.
First line antifungal therapy:
Oral fluconazole: 200-400 mg * 14-21 IV fluconazole: 400 mg daily (6mg/kg/day) AmB-d: 0.3-0.7 mg/day
In fluconazole refractory patients:
Itraconazole: 200 mg daily Voriconazole: 200 mg twice daily for 14-21 days Micafungin: 150 mg daily Caspofungin: 50 mg daily Anidu-lafungin: 200 mg daily AmB-d: 0.3 - 0.7 mg/kg daily
Prophylactic (suppressive) therapy:
Fluconazole 100-200 3 times/ week
HIV patients:
HAART therapy decreases recurrence of candida esophagitis.