Smoking pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
===Genetics=== | ===Genetics=== | ||
*CYP2A6 is the gene coding for enzymes that metabolize nicotine. Polymorphisms in the gene | *CYP2A6 is the gene coding for enzymes that metabolize nicotine. Polymorphisms in the gene can result in the variability in individual smoking response and addictive behavior by influencing the nicotine metabolism in the body .<ref name="pmid28507465">{{cite journal| author=López-Flores LA, Pérez-Rubio G, Falfán-Valencia R| title=Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction. | journal=EXCLI J | year= 2017 | volume= 16 | issue= | pages= 174-196 | pmid=28507465 | doi=10.17179/excli2016-847 | pmc=5427481 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28507465 }} </ref> | ||
==References== | ==References== | ||
Revision as of 16:03, 31 May 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Pathophysiology
Genetics
- CYP2A6 is the gene coding for enzymes that metabolize nicotine. Polymorphisms in the gene can result in the variability in individual smoking response and addictive behavior by influencing the nicotine metabolism in the body .[1]
References
- ↑ López-Flores LA, Pérez-Rubio G, Falfán-Valencia R (2017). "Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction". EXCLI J. 16: 174–196. doi:10.17179/excli2016-847. PMC 5427481. PMID 28507465.