Strongyloidiasis medical therapy: Difference between revisions
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===Antimicrobial Regimen=== | ===Antimicrobial Regimen=== | ||
*Strongyloides stercoralis <ref name="pmid8483992">{{cite journal| author=Archibald LK, Beeching NJ, Gill GV, Bailey JW, Bell DR| title=Albendazole is effective treatment for chronic strongyloidiasis. | journal=Q J Med | year= 1993 | volume= 86 | issue= 3 | pages= 191-5 | pmid=8483992 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8483992 }} </ref> | *Strongyloides stercoralis <ref name="pmid8483992">{{cite journal| author=Archibald LK, Beeching NJ, Gill GV, Bailey JW, Bell DR| title=Albendazole is effective treatment for chronic strongyloidiasis. | journal=Q J Med | year= 1993 | volume= 86 | issue= 3 | pages= 191-5 | pmid=8483992 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8483992 }} </ref> | ||
:* Preferred regimen: [[Ivermectin]] 200 mcg/kg/day PO qd for 2 days or two doses 2 weeks apart from each other<ref>{{Cite web | title = WGO Practice Guideline Management of Strongyloidiasis| url = http://www.worldgastroenterology.org/assets/downloads/en/pdf/guidelines/15_management_strongyloidiasis_en.pdf}}</ref> | :* Preferred regimen (1): [[Ivermectin]] 200 mcg/kg/day PO qd for 2 days or two doses 2 weeks apart from each other<ref>{{Cite web | title = WGO Practice Guideline Management of Strongyloidiasis| url = http://www.worldgastroenterology.org/assets/downloads/en/pdf/guidelines/15_management_strongyloidiasis_en.pdf}}</ref> | ||
:* Alternative regimen (1): [[Albendazole]] 400 mg PO bid for 3-7 days | :* Alternative regimen (1): [[Albendazole]] 400 mg PO bid for 3-7 days | ||
:* Alternative regimen (2): [[Nitazoxanide]] 500 mg bid for 3 days (adolescents and adults); 200mg bid for 3 days (children 4-11 yrs of age); 100mg PO bid for 3 days (children 1-3 yrs of age) | :* Alternative regimen (2): [[Nitazoxanide]] 500 mg bid for 3 days (adolescents and adults); 200mg bid for 3 days (children 4-11 yrs of age); 100mg PO bid for 3 days (children 1-3 yrs of age) | ||
Revision as of 13:23, 21 June 2017
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Strongyloidiasis Microchapters |
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Strongyloidiasis medical therapy On the Web |
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Risk calculators and risk factors for Strongyloidiasis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
The drug of choice for the treatment of uncomplicated strongyloidiasis is ivermectin with albendazole as the alternative. All patients who are at risk of disseminated strongyloidiasis should be treated.[1]
Treatment
All strongyloidiasis infection (symptomatic and asymptomatic) should be treated with antimicrobial therapy.[2] Due to the high rate of reinfection, it is sometimes necessary to repeat antimicrobial therapy
Antimicrobial Regimen
- Strongyloides stercoralis [2]
- Preferred regimen (1): Ivermectin 200 mcg/kg/day PO qd for 2 days or two doses 2 weeks apart from each other[3]
- Alternative regimen (1): Albendazole 400 mg PO bid for 3-7 days
- Alternative regimen (2): Nitazoxanide 500 mg bid for 3 days (adolescents and adults); 200mg bid for 3 days (children 4-11 yrs of age); 100mg PO bid for 3 days (children 1-3 yrs of age)
- Alternative regimen (3): Levamisole 150 mg PO single dose. The pediatric dose is 2.5 mg/kg PO daily
- Alternative regimen (4): Pyrantel pamoate 11 mg/kg single dose PO, maximum 1.0 g
- Alternative regimen (5): Piperazine citrate 75 mg/kg/day for 2 days, maximum 3.5 g/day
References
- ↑ http://www.dpd.cdc.gov/dpdx/HTML/Strongyloidiasis.htm
- ↑ Archibald LK, Beeching NJ, Gill GV, Bailey JW, Bell DR (1993). "Albendazole is effective treatment for chronic strongyloidiasis". Q J Med. 86 (3): 191–5. PMID 8483992.
- ↑ "WGO Practice Guideline Management of Strongyloidiasis" (PDF).