African trypanosomiasis differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
==Differentiating African trypnosomiasis ffrom otherdiseases== | ==Differentiating African trypnosomiasis ffrom otherdiseases== | ||
The hemo-lymphatic stage of African trympnosomiasis presents with a rash, fever and anemia and must be differentiated with other diseases such as [[brucellosis]], [[typhoid fever]], [[malaria]], [[tuberculosis]], [[lymphoma]], [[Dengue]], [[Leptospirosis]], | The hemo-lymphatic stage of African trympnosomiasis presents with a rash, fever and anemia and must be differentiated with other diseases such as [[brucellosis]], [[typhoid fever]], [[malaria]], [[tuberculosis]], [[lymphoma]], [[Dengue]], [[Leptospirosis]].<ref name="pmid1593042322">{{cite journal|author=Pappas G, Akritidis N, Bosilkovski M, Tsianos E|title=Brucellosis.|journal=N Engl J Med|year=2005|volume=352|issue=22|pages=2325-36|pmid=15930423|doi=10.1056/NEJMra050570|pmc=|url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15930423}}</ref><ref>Brucellosis "Dennis Kasper, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson, Joseph Loscalzo"Harrison's Principles of Internal Medicine, 19e Accessed on January,2017</ref><ref name="pmid754636422">{{cite journal|year=1995|title=Brucellosis: current epidemiology, diagnosis, and management.|url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7546364|journal=Curr Clin Top Infect Dis|volume=15|issue=|pages=115-28|doi=|pmc=|pmid=7546364|author=Young EJ}}</ref><ref name="enf22">Enfermedades infecciosas: Brucelosis -Diagnóstico de Brucelosis,Guia para el Equipo de Salud. Ministerio de Salud-Argentina. http://www.msal.gob.ar/images/stories/bes/graficos/0000000304cnt-guia-medica-brucelosis.pdf. Accessed on February 2, 2016</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
!Differential diagnosis of Brucellosis | !Differential diagnosis of Brucellosis |
Revision as of 13:43, 23 June 2017
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Overview
Differentiating African trypnosomiasis ffrom otherdiseases
The hemo-lymphatic stage of African trympnosomiasis presents with a rash, fever and anemia and must be differentiated with other diseases such as brucellosis, typhoid fever, malaria, tuberculosis, lymphoma, Dengue, Leptospirosis.[1][2][3][4]
Differential diagnosis of Brucellosis | Symptoms | Signs | Diagnosis | Additional Findings | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Fever | Rash | Diarrhea | Abdominal pain | Weight loss | Painful lymphadenopathy | Hepatosplenomegaly | Arthritis | Lab Findings | ||
Brucellosis | + | + | - | + | + | + | + | + | Relative lymphocytosis |
Night sweats, often with characteristic smell, likened to wet hay |
Typhoid fever | + | + | - | + | - | - | + | + | Decreased hemoglobin | Incremental increase in temperature initially and than sustained fever as high as 40°C (104°F) |
Malaria | + | - | + | + | - | - | + | + | Microcytosis,
elevated LDH |
"Tertian" fever: paroxysms occur every second day |
Tuberculosis | + | + | - | + | + | + | - | + | Mild normocytic anemia, hyponatremia, and | Night sweats, constant fatigue |
Lymphoma | + | - | - | + | + | - | + | - | Increase ESR, increased LDH | Night sweats, constant fatigue |
Mumps | + | - | - | - | - | + | - | - | Relative lymphocytosis, serum amylase elevated | Parotid swelling/tenderness |
HIV | - | - | - | + | + | + | - | + | Constant fatigue |
References
- ↑ Pappas G, Akritidis N, Bosilkovski M, Tsianos E (2005). "Brucellosis". N Engl J Med. 352 (22): 2325–36. doi:10.1056/NEJMra050570. PMID 15930423.
- ↑ Brucellosis "Dennis Kasper, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson, Joseph Loscalzo"Harrison's Principles of Internal Medicine, 19e Accessed on January,2017
- ↑ Young EJ (1995). "Brucellosis: current epidemiology, diagnosis, and management". Curr Clin Top Infect Dis. 15: 115–28. PMID 7546364.
- ↑ Enfermedades infecciosas: Brucelosis -Diagnóstico de Brucelosis,Guia para el Equipo de Salud. Ministerio de Salud-Argentina. http://www.msal.gob.ar/images/stories/bes/graficos/0000000304cnt-guia-medica-brucelosis.pdf. Accessed on February 2, 2016