Infected mosquito bite introduces the third stage larva onto the skin and then enters to the blood through the wound.
The larvae reside in the lymphatic vessels and mature to adult worms.
Adult worm produce sheathed microfiliae that migrate to lymph and blood.
Another mosquito ingests the microfiliae.
The microfilariae lose their sheaths and work their way through the wall of the proventriculus and cardiac portion of the midgut to reach the thoracic muscles
Microfiliae grow up inside the mosquito till third stage larvae.
In another bite to a host skin the mosquito introduces the larvae onto the skin.
The difference between the different nematodes causing lymphatic filariasis is in the shape and size of the worm.
The Brugia worms are similar to the W. bancrofti but smaller.
