Sandbox:Filariasis pathogenesis: Difference between revisions
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* Infected fly bite introduces the third stage larva onto the skin and then enters to the blood through the wound. | * Infected fly bite introduces the third stage larva onto the skin and then enters to the blood through the wound. | ||
* The larvae develop to adult which reside in the '''subcutaneous tissue'''. | * The larvae develop to adult which reside in the '''subcutaneous tissue'''. | ||
* | * Loa Loa adult worm produce sheathed microfilariae that are found in the blood during day and in the lungs during the non circulating phase. They have '''diurnal periodicity'''. | ||
* Another fly ingests the microfiliae. | * Another fly ingests the microfiliae. | ||
* After ingestion, the microfilariae lose their sheaths and migrate from the fly's [[midgut]] through the [[hemocoel]] to the thoracic muscles of the [[arthropod]]. | * After ingestion, the microfilariae lose their sheaths and migrate from the fly's [[midgut]] through the [[hemocoel]] to the thoracic muscles of the [[arthropod]]. | ||
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* Blackfly (genus Simulium) | * Blackfly (genus Simulium) | ||
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* Infected midge bite introduces the third stage larva onto the skin and then enters to the blood through the wound. | |||
* The larvae develop to adult which reside in the different body cavities like [[peritoneal cavity]], [[pleural cavity]], and less frequently in the [[pericardium]]. | |||
* Adult worm produce unsheathed subperiodic microfilariae that reaches the blood stream. | |||
* Another midge ingests microfilariae during a [[blood]] meal. | |||
* After [[ingestion]], the microfilariae migrate from the midge's [[midgut]] through the [[hemocoel]] to the thoracic muscles of the [[arthropod]]. | |||
* Microfiliae grow up inside the midge till third stage larvae. | |||
* The third-stage infective larvae migrate to the midge's proboscis and in another bite the cycle restarts. | |||
|[[Image:M perstans LifeCycle.gif|350 px|center]] | |[[Image:M perstans LifeCycle.gif|350 px|center]] | ||
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Life cycles of the roundworms causing filariasis: | Life cycles of the roundworms causing filariasis: |
Revision as of 15:18, 27 June 2017
Type of filariasis | Causative nematode | Vectors | Life cycle | Illustrative image | Comments |
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Lymphatic filariasis | Wuchereria bancrofti |
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Brugia timori and Brugia malayi |
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Subcutaneous filariasis | Loa loa filaria |
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Mansonella streptocerca |
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Mansonella ozzardi |
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Onchocerca volvulus |
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Serous cavity filariasis | Mansonella perstans |
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Life cycles of the roundworms causing filariasis: