Sandbox:Filariasis pathogenesis: Difference between revisions
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|Immune response of the host | |Immune response of the host | ||
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* In several studies, it has been noticed that there is a strong correlation between the host immune response and lymphoedema development. The immune response is higher in the lymphedema patients more than the patients with microfilariae just cirulating in the blood. | |||
* Hence, it is believed the role of the immune response in development of the lymphedema as it leads to inflammation and obstruction of the lymphatic vessels. | |||
* Infection by filariasis induces cell mediated immunity in response to the filarial antigens. This will lead to production of cytokines and interleukns. | |||
* High levels of immunoglobulins (IgG1,2,3) has been detected in patients with lymphedema which increases the evidence of the role of the immune response in pathogenesis of the disease. | |||
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|Secondary bacterial inections | |Secondary bacterial inections |
Revision as of 20:12, 27 June 2017
Factor | Role in pathogenesis |
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Immune response of the host |
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Secondary bacterial inections | |
Worm antigens accumulation | |
Wolbachia bacteria |