Echinococcosis pathophysiology: Difference between revisions
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*In 32 to 80 days after evagination the protoscolices develop into adult tape worm. | *In 32 to 80 days after evagination the protoscolices develop into adult tape worm. | ||
*The life cycle of [[E. multilocularis]] is similar to the life cycle of Echinococcus granulosus, but with the following differences: The definitive hosts are foxes, and to a lesser extent dogs, cats, coyotes and wolves. The intermediate host are small rodents and the larval growth (in the [[liver]]) remains indefinitely in the proliferative stage, resulting in invasion of the surrounding tissues. | *The life cycle of [[E. multilocularis]] is similar to the life cycle of Echinococcus granulosus, but with the following differences: The definitive hosts are foxes, and to a lesser extent dogs, cats, coyotes and wolves. The intermediate host are small rodents and the larval growth (in the [[liver]]) remains indefinitely in the proliferative stage, resulting in invasion of the surrounding tissues. | ||
* | *In the life cycle of E. vogeli the definitive hosts are bush dogs and dogs. The intermediate hosts are rodents and the larval stage in the [[liver]], [[lung]] develops both externally and internally, resulting in multiple vesicles. | ||
*E. oligarthrus (up to 2.9 mm long) has a life cycle that involves wild felids as definitive hosts and rodents as intermediate hosts. Humans become infected by ingesting eggs , with resulting release of oncospheres in the intestine and the development of cysts in various organs. | *E. oligarthrus (up to 2.9 mm long) has a life cycle that involves wild felids as definitive hosts and rodents as intermediate hosts. Humans become infected by ingesting eggs , with resulting release of oncospheres in the intestine and the development of cysts in various organs. | ||
Revision as of 17:28, 28 June 2017
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Echinococcosis Microchapters |
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Diagnosis |
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Treatment |
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Echinococcosis pathophysiology On the Web |
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American Roentgen Ray Society Images of Echinococcosis pathophysiology |
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Risk calculators and risk factors for Echinococcosis pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Kalsang Dolma, M.B.B.S.[3]
Pathophysiology
(1)The adult Echinococcus granulosus (2) Embryonated eggs (3) Oncosphere (4) Cyst (5) Protoscolices (6) Protoscolices evaginating.
Trasmission of infection
- The transmission of infection from the definitive host to the intermediate host occurs by the ingestion of embryonated eggs passed in the feces.
- The definitive host is infected by the ingestion of cyst containing organs of the infected intermediate host.
Pathogenesis
- The embronated eggs are excreted in the feces of the definitive host, which include dogs and other carnivores.
- The intermediate hosts include: sheep, cattle, horses and camel. Once ingested the eggs hatch in the small bowel and release oncospheres.
- The onchospheres penetrate the intestinal wall and migrate through the vascular system to organs such as liver and lung.
- In the lungs and liver the oncospheres develop into a cyst producing protoscolices and daughter cysts which fill the interior of the cyst.
- The definite host will be infected if they ingest the cyst containing organs.
- Once ingested the protoscolices evaginate and attach the intestinal mucosa.
- In 32 to 80 days after evagination the protoscolices develop into adult tape worm.
- The life cycle of E. multilocularis is similar to the life cycle of Echinococcus granulosus, but with the following differences: The definitive hosts are foxes, and to a lesser extent dogs, cats, coyotes and wolves. The intermediate host are small rodents and the larval growth (in the liver) remains indefinitely in the proliferative stage, resulting in invasion of the surrounding tissues.
- In the life cycle of E. vogeli the definitive hosts are bush dogs and dogs. The intermediate hosts are rodents and the larval stage in the liver, lung develops both externally and internally, resulting in multiple vesicles.
- E. oligarthrus (up to 2.9 mm long) has a life cycle that involves wild felids as definitive hosts and rodents as intermediate hosts. Humans become infected by ingesting eggs , with resulting release of oncospheres in the intestine and the development of cysts in various organs.
Gross Pathology
Shown below is an image of a typical cyst at removal.
