Hantavirus infection natural history, complications and prognosis: Difference between revisions
Usama Talib (talk | contribs) No edit summary |
Usama Talib (talk | contribs) m (Usama Talib moved page Hantavirus pulmonary syndrome natural history, complications and prognosis to Hantavirus infection natural history, complications and prognosis without leaving a redirect) |
||
| Line 6: | Line 6: | ||
==Natural History== | ==Natural History== | ||
Within 24 hours of initial evaluation, most patients develop some degree of [[hypotension]] and progressive evidence of [[pulmonary edema]] and [[hypoxia]], usually requiring mechanical ventilation. The patients with fatal infections appear to have severe myocardial depression which can progress to [[sinus bradycardia]] with subsequent [[electromechanical dissociation]], [[ventricular tachycardia]] or [[fibrillation]]. | *Within 24 hours of initial evaluation, most patients develop some degree of [[hypotension]] and progressive evidence of [[pulmonary edema]] and [[hypoxia]], usually requiring mechanical ventilation. The patients with fatal infections appear to have severe myocardial depression which can progress to [[sinus bradycardia]] with subsequent [[electromechanical dissociation]], [[ventricular tachycardia]] or [[fibrillation]]. | ||
Hemodynamic compromise occurs a median of 5 days after symptom onset--usually dramatically within the first day of hospitalization. In contrast to HFRS, overt hemorrhage occurs rarely in HPS, although hemorrhage is occasionally seen in association with disseminated intravascular coagulation. In contrast to septic shock, HPS patients have a low cardiac output with a raised systemic vascular resistance. Poor prognostic indicators include a plasma lactate of greater than 4.0 mmol/L or a cardiac index of less than 2.2 L/min/m2 Whilst pulmonary edema and pleural effusions are common, [[multiorgan dysfunction syndrome]] is rarely seen. However, HPS patients sometimes have mildly impaired renal function. Survivors frequently become polyuric during convalescence and improve almost as rapidly as they decompensated. | Hemodynamic compromise occurs a median of 5 days after symptom onset--usually dramatically within the first day of hospitalization. In contrast to HFRS, overt hemorrhage occurs rarely in HPS, although hemorrhage is occasionally seen in association with disseminated intravascular coagulation. In contrast to septic shock, HPS patients have a low cardiac output with a raised systemic vascular resistance. Poor prognostic indicators include a plasma lactate of greater than 4.0 mmol/L or a cardiac index of less than 2.2 L/min/m2 Whilst pulmonary edema and pleural effusions are common, [[multiorgan dysfunction syndrome]] is rarely seen. However, HPS patients sometimes have mildly impaired renal function. Survivors frequently become polyuric during convalescence and improve almost as rapidly as they decompensated. | ||
Revision as of 15:57, 7 July 2017
|
Hantavirus infection Microchapters |
|
Patient Information |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Hantavirus infection natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Hantavirus infection natural history, complications and prognosis |
|
FDA on Hantavirus infection natural history, complications and prognosis |
|
CDC on Hantavirus infection natural history, complications and prognosis |
|
Hantavirus infection natural history, complications and prognosis in the news |
|
Blogs on Hantavirus infection natural history, complications and prognosis |
|
Directions to Hospitals Treating Hantavirus pulmonary syndrome |
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Natural History
- Within 24 hours of initial evaluation, most patients develop some degree of hypotension and progressive evidence of pulmonary edema and hypoxia, usually requiring mechanical ventilation. The patients with fatal infections appear to have severe myocardial depression which can progress to sinus bradycardia with subsequent electromechanical dissociation, ventricular tachycardia or fibrillation.
Hemodynamic compromise occurs a median of 5 days after symptom onset--usually dramatically within the first day of hospitalization. In contrast to HFRS, overt hemorrhage occurs rarely in HPS, although hemorrhage is occasionally seen in association with disseminated intravascular coagulation. In contrast to septic shock, HPS patients have a low cardiac output with a raised systemic vascular resistance. Poor prognostic indicators include a plasma lactate of greater than 4.0 mmol/L or a cardiac index of less than 2.2 L/min/m2 Whilst pulmonary edema and pleural effusions are common, multiorgan dysfunction syndrome is rarely seen. However, HPS patients sometimes have mildly impaired renal function. Survivors frequently become polyuric during convalescence and improve almost as rapidly as they decompensated.