Congenital adrenal hyperplasia epidemiology and demographics: Difference between revisions
| Line 7: | Line 7: | ||
== Epidemiology and Demographics == | == Epidemiology and Demographics == | ||
The classic type affects approximately 1 in 16,000 live births.2 NCCAH is one of the most common autosomal recessive disorders in humans and affects approximately 1 in 1000 individuals.3 The second most common form of CAH, 11b-hydroxylase deficiency (11-OHD), occurs in 1 in 100,000 live births in the general population and accounts for approximately 5% of cases.4 Other less common forms of CAH include 3b-hydroxysteroid dehydrogenase type 2 deficiency, 17a-hydroxylase deficiency that is more commonly seen in Brazil and Mennonite descendants from Dutch Friesland; congenital lipoid adrenal hyperplasia that is more commonly seen in the Japanese and Korean populations; side-chain cleavage (SCC) enzyme deficiency that is most commonly found in Turkey; and cytochrome P450 oxidoreductase deficiency, the only variant that can manifest with skeletal malformation | The classic type affects approximately 1 in 16,000 live births.2 | ||
NCCAH is one of the most common autosomal recessive disorders in humans and affects approximately 1 in 1000 individuals.3 | |||
The second most common form of CAH, 11b-hydroxylase deficiency (11-OHD), occurs in 1 in 100,000 live births in the general population and accounts for approximately 5% of cases.4 | |||
Other less common forms of CAH include 3b-hydroxysteroid dehydrogenase type 2 deficiency, 17a-hydroxylase deficiency that is more commonly seen in Brazil and Mennonite descendants from Dutch Friesland; congenital lipoid adrenal hyperplasia that is more commonly seen in the Japanese and Korean populations; side-chain cleavage (SCC) enzyme deficiency that is most commonly found in Turkey; and cytochrome P450 oxidoreductase deficiency, the only variant that can manifest with skeletal malformation | |||
CAH ART | CAH ART | ||
Revision as of 18:09, 7 July 2017
|
Congenital adrenal hyperplasia main page |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Epidemiology and Demographics
The classic type affects approximately 1 in 16,000 live births.2
NCCAH is one of the most common autosomal recessive disorders in humans and affects approximately 1 in 1000 individuals.3
The second most common form of CAH, 11b-hydroxylase deficiency (11-OHD), occurs in 1 in 100,000 live births in the general population and accounts for approximately 5% of cases.4
Other less common forms of CAH include 3b-hydroxysteroid dehydrogenase type 2 deficiency, 17a-hydroxylase deficiency that is more commonly seen in Brazil and Mennonite descendants from Dutch Friesland; congenital lipoid adrenal hyperplasia that is more commonly seen in the Japanese and Korean populations; side-chain cleavage (SCC) enzyme deficiency that is most commonly found in Turkey; and cytochrome P450 oxidoreductase deficiency, the only variant that can manifest with skeletal malformation
CAH ART