Hantavirus infection epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Epidemiology

Incidence

• Total number of HPS cases reported in the United States from 1993-2003 is 336
• Total number of HPS cases reported in the United States from 2004-2015 is 323
• The annual incidence of HPS in Europe is 3,000 per 100,000 persons.

Demographics

Age

The mean age of confirmed case patients is 38 years (range: 5 to 84 years).

Gender

Men and women are affected equally by hantavirus infection but of persons ill with hantavirus cardiopulmonary syndrome, 63% have been male, 37% female.

Race

There is no racial predilection for hantavirus infection. However, Whites currently account for 78% of all cases. American Indians account for about 18% of cases, African Americans for 1% of cases, and Asians for 1% of cases. Of cases with known ethnicity, 19% of HPS cases have been reported among Hispanics (ethnicity considered separately from race).

Geographic distrubution

• Of 659 cases reported, 96% occurred in states west of the Mississippi River, most of which were infected with SNV.

Hantavirus Pulmonary Syndrome Case Count and Descriptive Statistics in the U.S.

• Through March 26, 2007, a total of 465 cases of hantavirus pulmonary syndrome have been reported in the United States. The case count started when the disease was first recognized in May 1993. Thirty-five percent of all reported cases have resulted in death.
• Of persons ill with HPS, 64% have been male, 37% female.
• The mean age of confirmed case patients is 38 years (range: 10 to 83 years).
• HPS can strike anyone; however, whites currently account for 78% of all cases. American Indians account for about 19% of cases, African Americans for 2% of cases, and Asians for 1% of cases. About 14% of HPS cases have been reported among Hispanics (ethnicity considered separately from race).
• Cases have been reported in 30 states, including most of the western half of the country and some eastern states as well. Over half of the confirmed cases have been reported from areas outside the Four Corners area.
• About three-quarters of patients with HPS have been residents of rural areas.

Hantavirus pulmonary syndrome cases by outcome between January 1993 and March 26, 2007