Heparin-induced thrombocytopenia diagnostic criteria: Difference between revisions
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{{Heparin-induced thrombocytopenia}} | {{Heparin-induced thrombocytopenia}} | ||
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==Overview== | ==Overview== | ||
==Diagnostic Criteria== | |||
===The 4T score=== | ===The 4T score=== | ||
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The American Society of Hematology, as part of the [http://www.choosingwisely.org/ Choosing Wisely] program, states<ref>The American Society of Hematology. [http://www.choosingwisely.org/clinician-lists/american-society-hematology-testing-treating-suspected-heparin-induced-thrombocytopenia/Don’t test or treat for suspected heparin-induced thrombocytopenia (HIT) in patients with a low pre-test probability of HIT.]. 2014</ref>: | The American Society of Hematology, as part of the [http://www.choosingwisely.org/ Choosing Wisely] program, states<ref>The American Society of Hematology. [http://www.choosingwisely.org/clinician-lists/american-society-hematology-testing-treating-suspected-heparin-induced-thrombocytopenia/Don’t test or treat for suspected heparin-induced thrombocytopenia (HIT) in patients with a low pre-test probability of HIT.]. 2014</ref>: | ||
: "Don’t test or treat for suspected heparin-induced thrombocytopenia (HIT) in patients with a low pre-test probability of HIT." | : "Don’t test or treat for suspected heparin-induced thrombocytopenia (HIT) in patients with a low pre-test probability of HIT." | ||
Revision as of 22:45, 9 July 2017
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Heparin-induced thrombocytopenia |
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Differentiating Heparin-induced thrombocytopenia from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Shyam Patel [2]
Overview
Diagnostic Criteria
The 4T score
The current diagnostic algorithm for HIT involves calculation of the pre-test probability using the 4T score. This scoring system is used when a patient is found to have thrombocytopenia or thrombosis after heparin exposure. It is calculated before the heparin-PF4 IgG antibody is ordered, and it offers a cost-effective and efficient way for determining the likelihood of HIT.[1]
- Thrmobocytopenia
- Thrombosis
- Timing
- oTher
- 0 to 3 points: low probability
- 4 to 5 points: intermediate probability
- 6 to 8 points: high probability
The American Society of Hematology, as part of the Choosing Wisely program, states[3]:
- "Don’t test or treat for suspected heparin-induced thrombocytopenia (HIT) in patients with a low pre-test probability of HIT."
Reference
- ↑ Gardiner EE, Andrews RK, Cuker A (2014). "DiagnoSTic assays for heparin-induced thrombocytopenia". Br J Haematol. 166 (5): 631–3. doi:10.1111/bjh.12940. PMC 4134688. PMID 24824208.
- ↑ Cuker A, Gimotty PA, Crowther MA, Warkentin TE (2012). "Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis". Blood. 120 (20): 4160–7. doi:10.1182/blood-2012-07-443051. PMC 3501714. PMID 22990018.
- ↑ The American Society of Hematology. test or treat for suspected heparin-induced thrombocytopenia (HIT) in patients with a low pre-test probability of HIT.. 2014