Primary hyperaldosteronism differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
== | ==Differentiating Conn's Syndrome From Other Diseases== | ||
Conn's syndrome should be differentiated from other diseases causing hypertension and hypokalemia for example: | Conn's syndrome should be differentiated from other diseases causing hypertension and hypokalemia for example: | ||
*Renal artery stenosis | *Renal artery stenosis | ||
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{{familytree | | | | | | | | | B01 | | | | | |B01=Plasma renin activity}} | {{familytree | | | | | | | | | B01 | | | | | |B01=Plasma renin activity}} | ||
{{familytree | | |,|-|-|-|-|-|-|^|-|-|-|-|-|-|.| }} | {{familytree | | |,|-|-|-|-|-|-|^|-|-|-|-|-|-|.| }} | ||
{{familytree | | C01 | | | | | | | | | | | |C02|C01=Normal or High|C02=Suppressed}} | {{familytree | | C01 | | | | | | | | | | | |C02|C01=Normal or High (Plasma Renin/Aldosterone ratio <10|C02=Suppressed (Plasme Renin/Aldosterone ratio >20}} | ||
{{familytree | | |!| | | | | | | | | | | | | |!| }} | {{familytree | | |!| | | | | | | | | | | | | |!| }} | ||
{{familytree | | D01 | | | | | | | | | | | |D02|D01= | {{familytree | | D01 | | | | | | | | | | | |D02|D01=*Renin-secreting tumors<br>*Diuretic use<br>*Renovascular hypertension<br>*Coarctation of aorta<br>*Malignant phase hypertension|D02=Urinary aldosterone}} | ||
{{familytree | | | | | | | | | | | | |,|-|-|-|+|-|-|-|-|.|}} | {{familytree | | | | | | | | | | | | |,|-|-|-|+|-|-|-|-|.|}} | ||
{{familytree | | | | | | | | | | | | E01 | | E02 | | | E03 |E01=Elevated|E02=Normal|E03=Low|}} | {{familytree | | | | | | | | | | | | E01 | | E02 | | | E03 |E01=Elevated|E02=Normal|E03=Low|}} | ||
Revision as of 23:32, 9 July 2017
Overview
Differentiating Conn's Syndrome From Other Diseases
Conn's syndrome should be differentiated from other diseases causing hypertension and hypokalemia for example:
- Renal artery stenosis
- Cushing's syndrome
- Congenital adrenal hyperplasia (CAH)
- 17 alpha hydroxylase deficiency
- 11 beta hydroxylase deficiency
- Liddle's syndrome
- Diuretic use
- Licorice ingestion
- Renin-secreting tumors
| Hypertension and Hypokalemia | |||||||||||||||||||||||||||||||||||||||||||||||
| Plasma renin activity | |||||||||||||||||||||||||||||||||||||||||||||||
| Normal or High (Plasma Renin/Aldosterone ratio <10 | Suppressed (Plasme Renin/Aldosterone ratio >20 | ||||||||||||||||||||||||||||||||||||||||||||||
| *Renin-secreting tumors *Diuretic use *Renovascular hypertension *Coarctation of aorta *Malignant phase hypertension | Urinary aldosterone | ||||||||||||||||||||||||||||||||||||||||||||||
| Elevated | Normal | Low | |||||||||||||||||||||||||||||||||||||||||||||
| Conn's syndrome (Primary aldosteronism) | Profound K+ depletion | • 17 alpha hydroxylase deficiency • 11 beta hydroxylase deficiency • Liddle's syndrome • Licorice ingestion • Deoxycortisone producing tumor | |||||||||||||||||||||||||||||||||||||||||||||