Pheochromocytoma risk factors: Difference between revisions
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Occurs in third to fifth decades of life; the average age at diagnosis is 24.9 years in hereditary cases and 43.9 years in sporadic cases. Hereditary tumors present at a younger age than sporadic. | Occurs in third to fifth decades of life; the average age at diagnosis is 24.9 years in hereditary cases and 43.9 years in sporadic cases.<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015. National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_25_toc</ref> | ||
Hereditary tumors present at a younger age than sporadic. | |||
=== '''Family history:''' === | === '''Family history:''' === | ||
Revision as of 15:35, 10 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]}
Overview
Pheochromocytoma is more common in people between 40 and 60 years old, men, people with family history of multiple endocrine neoplasia, von Hippel-Lindau disease, neurofibromatosis 1, hereditary paraganglioma syndromes.
Risk Factors
The most portent risk factors of pheochromocytoma are:
Age:
Occurs in third to fifth decades of life; the average age at diagnosis is 24.9 years in hereditary cases and 43.9 years in sporadic cases.[1]
Hereditary tumors present at a younger age than sporadic.
Family history:
Ten percent of pheochromocytomas are linked to hereditary causes:
- Multiple endocrine neoplasia type 2 is a hereditary condition associated with medullary thyroid cancer and other types of cancer, including pheochromocytoma.
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- Von Hippel-Lindau disease can result in tumors at multiple sites, including the central nervous system, endocrine system, pancreas and kidneys.
- Neurofibromatosis 1 (NF1) results in multiple tumors in the skin (neurofibromas), pigmented skin spots and tumors of the optic nerve.
- Hereditary paraganglioma syndromes are inherited disorders that result in either pheochromocytomas or paragangliomas.
References
- ↑ National Cancer Institute. Physician Data Query Database 2015. National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_25_toc