Zollinger-Ellison syndrome causes: Difference between revisions

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The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by  multiple endocrine neoplasia type 1 ([[MEN1]]).<ref name="NIDDK">National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes</ref>  
The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by  multiple endocrine neoplasia type 1 ([[MEN1]]).<ref name="NIDDK">National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes</ref>  
==Causes==
==Causes==
The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by  multiple endocrine neoplasia type 1 ([[MEN1]]).<ref name="NIDDK">National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes</ref>
*The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by  multiple endocrine neoplasia type 1 ([[MEN1]]).<ref name="NIDDK">National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes</ref>
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*Causes of Hypergastrinemia: <ref name="pmid21806955">{{cite journal| author=Metz DC| title=Diagnosis of the Zollinger–Ellison syndrome. | journal=Clin Gastroenterol Hepatol | year= 2012 | volume= 10 | issue= 2 | pages= 126-30 | pmid=21806955 | doi=10.1016/j.cgh.2011.07.012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21806955  }} </ref>
| '''Causes of Hypergastrinemia''' <ref name="pmid21806955">{{cite journal| author=Metz DC| title=Diagnosis of the Zollinger–Ellison syndrome. | journal=Clin Gastroenterol Hepatol | year= 2012 | volume= 10 | issue= 2 | pages= 126-30 | pmid=21806955 | doi=10.1016/j.cgh.2011.07.012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21806955  }} </ref>
 
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| colspan="3" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|'''Causes of Hypergastrinemia'''}}
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|'''Appropriate hypergastrinemia'''
|'''Appropriate hypergastrinemia'''
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Revision as of 16:16, 20 July 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by multiple endocrine neoplasia type 1 (MEN1).[1]

Causes

  • The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by multiple endocrine neoplasia type 1 (MEN1).[1]
  • Causes of Hypergastrinemia: [2]
Causes of Hypergastrinemia
Appropriate hypergastrinemia
Atrophic gastritis with or without pernicious anemia
Antisecretory therapy (PPIs or high-dose histamine H2-receptor antagonist)
Chronic renal failure
H pylori pangastritis
Vagotomy
Inappropriate hypergastrinemia
ZES (sporadic or associated with MEN-1)
Antral-predominant H pylori infection
Retained-antrum syndrome
Gastric-outlet obstruction
Small-bowel resection
Spurious hypergastrinemia
Nonfasting patient
Inaccurate assay

References

  1. 1.0 1.1 National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes
  2. Metz DC (2012). "Diagnosis of the Zollinger–Ellison syndrome". Clin Gastroenterol Hepatol. 10 (2): 126–30. doi:10.1016/j.cgh.2011.07.012. PMID 21806955.

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