Hashimoto's thyroiditis natural history, complications and prognosis: Difference between revisions
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Hashimoto's thyroiditis usually begins slowly and may progress to hypothyroidism. Complications include heart failure, lymphoma, and encephalopathy. | Hashimoto's thyroiditis usually begins slowly and may progress to hypothyroidism. Complications include heart failure, lymphoma, and encephalopathy. | ||
== Natural History== | == Natural History== | ||
The disease begins slowly. It may take months or even years for the condition to be detected. If untreated Hashimoto's thyroiditis may lead to muscle failure including heart failure and other features associated with hypothyroidism. | The disease begins slowly. It may take months or even years for the condition to be detected. If untreated Hashimoto's thyroiditis may lead to muscle failure including heart failure and other features associated with hypothyroidism.<ref name="pmid24434360">{{cite journal |vauthors=Caturegli P, De Remigis A, Rose NR |title=Hashimoto thyroiditis: clinical and diagnostic criteria |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=391–7 |year=2014 |pmid=24434360 |doi=10.1016/j.autrev.2014.01.007 |url=}}</ref> | ||
==Complications== | ==Complications== | ||
Complications that can develop as a result of Hashimoto's thyroiditis are: | Complications that can develop as a result of Hashimoto's thyroiditis are:<ref name="pmid24434360">{{cite journal |vauthors=Caturegli P, De Remigis A, Rose NR |title=Hashimoto thyroiditis: clinical and diagnostic criteria |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=391–7 |year=2014 |pmid=24434360 |doi=10.1016/j.autrev.2014.01.007 |url=}}</ref><ref name="pmid25027262">{{cite journal |vauthors=Kirshner HS |title=Hashimoto's encephalopathy: a brief review |journal=Curr Neurol Neurosci Rep |volume=14 |issue=9 |pages=476 |year=2014 |pmid=25027262 |doi=10.1007/s11910-014-0476-2 |url=}}</ref><ref name="pmid23300224">{{cite journal |vauthors=Lun Y, Wu X, Xia Q, Han Y, Zhang X, Liu Z, Wang F, Duan Z, Xin S, Zhang J |title=Hashimoto's thyroiditis as a risk factor of papillary thyroid cancer may improve cancer prognosis |journal=Otolaryngol Head Neck Surg |volume=148 |issue=3 |pages=396–402 |year=2013 |pmid=23300224 |doi=10.1177/0194599812472426 |url=}}</ref> | ||
*Hypothyroidism | *Hypothyroidism | ||
*Hyperthyroidism | *Hyperthyroidism | ||
*Heart failure | *Heart failure | ||
*Myxedema coma | |||
*Tracheal and/or esophageal compression | |||
*Hashimoto encephalopathy | *Hashimoto encephalopathy | ||
*Thyroid lymphoma | *Thyroid lymphoma | ||
Revision as of 17:22, 20 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
Hashimoto's thyroiditis usually begins slowly and may progress to hypothyroidism. Complications include heart failure, lymphoma, and encephalopathy.
Natural History
The disease begins slowly. It may take months or even years for the condition to be detected. If untreated Hashimoto's thyroiditis may lead to muscle failure including heart failure and other features associated with hypothyroidism.[1]
Complications
Complications that can develop as a result of Hashimoto's thyroiditis are:[1][2][3]
- Hypothyroidism
- Hyperthyroidism
- Heart failure
- Myxedema coma
- Tracheal and/or esophageal compression
- Hashimoto encephalopathy
- Thyroid lymphoma
Prognosis
The outcome is usually very good. The disease stays stable for years. If it does slowly progress to thyroid hormone deficiency (hypothyroidism), it can be treated with thyroid replacement therapy.
References
- ↑ 1.0 1.1 Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.
- ↑ Kirshner HS (2014). "Hashimoto's encephalopathy: a brief review". Curr Neurol Neurosci Rep. 14 (9): 476. doi:10.1007/s11910-014-0476-2. PMID 25027262.
- ↑ Lun Y, Wu X, Xia Q, Han Y, Zhang X, Liu Z, Wang F, Duan Z, Xin S, Zhang J (2013). "Hashimoto's thyroiditis as a risk factor of papillary thyroid cancer may improve cancer prognosis". Otolaryngol Head Neck Surg. 148 (3): 396–402. doi:10.1177/0194599812472426. PMID 23300224.