Differentiating Hashimoto's thyroiditis from other diseases: Difference between revisions

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Revision as of 14:41, 21 July 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S [2]

Hashimoto's thyroiditis must be differentiated from other causes of thyroiditis, such as DeQuervain's thyroiditis, Riedel's thyroiditis, and suppurative thyroiditis.^[1]

Conditions	Causes	Age at onset	Pathological findings	Diagnostic approach
Hashimoto's thyroiditis	Autoimmune	All ages, peak at 30-50	Lymphocytic infiltration Germinal centers Fibrosis (in some variants)	Increased TSH (hypothyroidism) TPO antibodies present in high titer Usually decreased I-123 uptake
Painful subacute (DeQuervain's) thyroiditis	Unknown	20-60	Giant cells Granulomas	Increased TSH (hypothyroidism) and/or Decreased TSH (Thyrotoxicosis) TPO antibodies absent or very low titer I-123 uptake decreased
Riedels thyroiditis	Unknown	30-60	Dense fibrosis	Normal TSH (euthyroidism) TPO antibodies present I-123 uptake decreased or normal
Suppurative thyroiditis	Infection	Children, 20-40	Abscess formation	Normal TSH (euthyroidism) TPO antibodies absent I-123 uptake normal

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 ==Differentiating Hashimoto's Thyroiditis from other Diseases==
-*Hashimoto's thyroiditis must be differentiated from other causes of thyroiditis, such as DeQuervain's thyroiditis, Riedel's thyroiditis, and suppurative thyroiditis.[[Lymphoma]] and [[depression]] may also present similarly to Hashimoto's thyroiditis.<ref name="urlThyroiditis — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJMra021194 |title=Thyroiditis — NEJM |format= |work= |accessdate=}}</ref>
+*Hashimoto's thyroiditis must be differentiated from other causes of thyroiditis, such as DeQuervain's thyroiditis, Riedel's thyroiditis, and suppurative thyroiditis.<ref name="urlThyroiditis — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJMra021194 |title=Thyroiditis — NEJM |format= |work= |accessdate=}}</ref>
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 ==References==