Psoriasis Screening: Difference between revisions
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===Genetic screening for psoriasis=== | ===Genetic screening for psoriasis=== | ||
*The strong association of psoriasis with [[genetics]] gives way to screening for this disease via genetic testing. | *The strong association of psoriasis with [[genetics]] gives way to screening for this disease via genetic testing. | ||
*[[HLA]] Class I antigens (HLA-B13, HLA-B57, HLA-B39, HLA-Cw6, HLACw7) have been known to be associated with psoriasis and psoriatic arthritis.<ref name="pmid12508382">{{cite journal |vauthors=Gladman DD, Farewell VT |title=HLA studies in psoriatic arthritis: current situation and future needs |journal=J. Rheumatol. |volume=30 |issue=1 |pages=4–6 |year=2003 |pmid=12508382 |doi= |url=}}</ref> | *[[HLA]] Class I antigens ([[HLA-B13]], HLA-B57, HLA-B39, HLA-Cw6, HLACw7) have been known to be associated with psoriasis and [[psoriatic arthritis]].<ref name="pmid12508382">{{cite journal |vauthors=Gladman DD, Farewell VT |title=HLA studies in psoriatic arthritis: current situation and future needs |journal=J. Rheumatol. |volume=30 |issue=1 |pages=4–6 |year=2003 |pmid=12508382 |doi= |url=}}</ref> | ||
*HLA-B13, -B16, and its splits -B38 and -B39, B17, and Cw6 are associated with psoriasis, with or without arthritis. | *[[HLA-B13]], -B16, and its splits -B38 and -B39, B17, and Cw6 are associated with psoriasis, with or without arthritis. | ||
*Early screening combined with early treatment can help prevent disease progression. | *Early screening combined with early treatment can help prevent disease progression. | ||
*A sample for [[genetic testing]] is usually taken from a cheek swab. | *A sample for [[genetic testing]] is usually taken from a cheek swab. | ||
===Psoriasis screening tool (PST)=== | ===Psoriasis screening tool (PST)=== | ||
*The Psoriasis Screening Tool (PST) consists of eight close ended questions with a "yes" or "no" response with typical images of skin, nail and scalp changes in psoriasis included with respective questions.<ref name="pmid19566664">{{cite journal |vauthors=Dominguez PL, Assarpour A, Kuo H, Holt EW, Tyler S, Qureshi AA |title=Development and pilot-testing of a psoriasis screening tool |journal=Br. J. Dermatol. |volume=161 |issue=4 |pages=778–84 |year=2009 |pmid=19566664 |doi=10.1111/j.1365-2133.2009.09247.x |url=}}</ref> | *The Psoriasis Screening Tool (PST) consists of eight close ended questions with a "yes" or "no" response with typical images of [[skin]], [[Nail (anatomy)|nail]] and [[scalp]] changes in psoriasis included with respective questions.<ref name="pmid19566664">{{cite journal |vauthors=Dominguez PL, Assarpour A, Kuo H, Holt EW, Tyler S, Qureshi AA |title=Development and pilot-testing of a psoriasis screening tool |journal=Br. J. Dermatol. |volume=161 |issue=4 |pages=778–84 |year=2009 |pmid=19566664 |doi=10.1111/j.1365-2133.2009.09247.x |url=}}</ref> | ||
*The questions distinguish individuals with psoriasis from individuals without the disease in an [[Outpatient|outpatient setting]]. | *The questions distinguish individuals with psoriasis from individuals without the disease in an [[Outpatient|outpatient setting]]. | ||
*A similar questionnaire exists for psoriatic arthritis, called the Psoriasis Epidemiology Screening Tool (PEST).<ref name="urlPsoriasis Epidemiology Screening Tool (PEST): A Report from the GRAPPA 2009 Annual Meeting | The Journal of Rheumatology">{{cite web |url=http://www.jrheum.org/content/38/3/551.long |title=Psoriasis Epidemiology Screening Tool (PEST): A Report from the GRAPPA 2009 Annual Meeting | The Journal of Rheumatology |format= |work= |accessdate=}}</ref> | *A similar questionnaire exists for [[psoriatic arthritis]], called the Psoriasis Epidemiology Screening Tool (PEST).<ref name="urlPsoriasis Epidemiology Screening Tool (PEST): A Report from the GRAPPA 2009 Annual Meeting | The Journal of Rheumatology">{{cite web |url=http://www.jrheum.org/content/38/3/551.long |title=Psoriasis Epidemiology Screening Tool (PEST): A Report from the GRAPPA 2009 Annual Meeting | The Journal of Rheumatology |format= |work= |accessdate=}}</ref> | ||
==References== | ==References== | ||
Revision as of 19:08, 24 July 2017
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American Roentgen Ray Society Images of Psoriasis Screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
There is no consensus for screening for psoriasis among the general population but there are screening tools, which can be used for psoriasis, for example, the psoriasis screening tool (PST) and genetic testing is recommended.
Screening
Genetic screening for psoriasis
- The strong association of psoriasis with genetics gives way to screening for this disease via genetic testing.
- HLA Class I antigens (HLA-B13, HLA-B57, HLA-B39, HLA-Cw6, HLACw7) have been known to be associated with psoriasis and psoriatic arthritis.[1]
- HLA-B13, -B16, and its splits -B38 and -B39, B17, and Cw6 are associated with psoriasis, with or without arthritis.
- Early screening combined with early treatment can help prevent disease progression.
- A sample for genetic testing is usually taken from a cheek swab.
Psoriasis screening tool (PST)
- The Psoriasis Screening Tool (PST) consists of eight close ended questions with a "yes" or "no" response with typical images of skin, nail and scalp changes in psoriasis included with respective questions.[2]
- The questions distinguish individuals with psoriasis from individuals without the disease in an outpatient setting.
- A similar questionnaire exists for psoriatic arthritis, called the Psoriasis Epidemiology Screening Tool (PEST).[3]
References
- ↑ Gladman DD, Farewell VT (2003). "HLA studies in psoriatic arthritis: current situation and future needs". J. Rheumatol. 30 (1): 4–6. PMID 12508382.
- ↑ Dominguez PL, Assarpour A, Kuo H, Holt EW, Tyler S, Qureshi AA (2009). "Development and pilot-testing of a psoriasis screening tool". Br. J. Dermatol. 161 (4): 778–84. doi:10.1111/j.1365-2133.2009.09247.x. PMID 19566664.
- ↑ "Psoriasis Epidemiology Screening Tool (PEST): A Report from the GRAPPA 2009 Annual Meeting | The Journal of Rheumatology".