Hypoglycemia other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
* In the case of failed imaging | * In the case of failed imaging investigations to diagnose insulinoma, calcium gluconate injection test is done, | ||
* | * The test can be performed to distinguish between insulinoma and islet-cell hypertrophy. | ||
* Injection of calcium gluconate into splanchnic arteries and venous sampling searching for insulin.<ref name="pmid26312578">{{cite journal| author=Thompson SM, Vella A, Thompson GB, Rumilla KM, Service FJ, Grant CS et al.| title=Selective Arterial Calcium Stimulation With Hepatic Venous Sampling Differentiates Insulinoma From Nesidioblastosis. | journal=J Clin Endocrinol Metab | year= 2015 | volume= 100 | issue= 11 | pages= 4189-97 | pmid=26312578 | doi=10.1210/jc.2015-2404 | pmc=4702445 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26312578 }}</ref> | * Injection of calcium gluconate into splanchnic arteries and venous sampling searching for insulin.<ref name="pmid26312578">{{cite journal| author=Thompson SM, Vella A, Thompson GB, Rumilla KM, Service FJ, Grant CS et al.| title=Selective Arterial Calcium Stimulation With Hepatic Venous Sampling Differentiates Insulinoma From Nesidioblastosis. | journal=J Clin Endocrinol Metab | year= 2015 | volume= 100 | issue= 11 | pages= 4189-97 | pmid=26312578 | doi=10.1210/jc.2015-2404 | pmc=4702445 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26312578 }}</ref> | ||
* In insulinoma, test is positive in one artery alone. | * In insulinoma, the test is positive in one artery alone. | ||
* Islet-cell hypertrophy, test is positive is positive in multiple arteries.<ref name="pmid25873534">{{cite journal| author=Thompson SM, Vella A, Service FJ, Grant CS, Thompson GB, Andrews JC| title=Impact of variant pancreatic arterial anatomy and overlap in regional perfusion on the interpretation of selective arterial calcium stimulation with hepatic venous sampling for preoperative localization of occult insulinoma. | journal=Surgery | year= 2015 | volume= 158 | issue= 1 | pages= 162-72 | pmid=25873534 | doi=10.1016/j.surg.2015.03.004 | pmc=4461470 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25873534 }}</ref> | * Islet-cell hypertrophy, the test is positive is positive in multiple arteries.<ref name="pmid25873534">{{cite journal| author=Thompson SM, Vella A, Service FJ, Grant CS, Thompson GB, Andrews JC| title=Impact of variant pancreatic arterial anatomy and overlap in regional perfusion on the interpretation of selective arterial calcium stimulation with hepatic venous sampling for preoperative localization of occult insulinoma. | journal=Surgery | year= 2015 | volume= 158 | issue= 1 | pages= 162-72 | pmid=25873534 | doi=10.1016/j.surg.2015.03.004 | pmc=4461470 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25873534 }}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 19:16, 24 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
Overview
Other tests include: injection of calcium gluconate into splanchnic arteries and venous sampling searching for insulin.[1]
Other Diagnostic Studies
- In the case of failed imaging investigations to diagnose insulinoma, calcium gluconate injection test is done,
- The test can be performed to distinguish between insulinoma and islet-cell hypertrophy.
- Injection of calcium gluconate into splanchnic arteries and venous sampling searching for insulin.[1]
- In insulinoma, the test is positive in one artery alone.
- Islet-cell hypertrophy, the test is positive is positive in multiple arteries.[2]
References
- ↑ Thompson SM, Vella A, Thompson GB, Rumilla KM, Service FJ, Grant CS; et al. (2015). "Selective Arterial Calcium Stimulation With Hepatic Venous Sampling Differentiates Insulinoma From Nesidioblastosis". J Clin Endocrinol Metab. 100 (11): 4189–97. doi:10.1210/jc.2015-2404. PMC 4702445. PMID 26312578.
- ↑ Thompson SM, Vella A, Service FJ, Grant CS, Thompson GB, Andrews JC (2015). "Impact of variant pancreatic arterial anatomy and overlap in regional perfusion on the interpretation of selective arterial calcium stimulation with hepatic venous sampling for preoperative localization of occult insulinoma". Surgery. 158 (1): 162–72. doi:10.1016/j.surg.2015.03.004. PMC 4461470. PMID 25873534.