Dermatophytosis other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Most of the time, ringworm can be diagnosed by looking at the skin. Other diagnostic studies that can be used to diagnose dermatophytosis are matrix-assisted laser desorption ionization | Most of the time, ringworm can be diagnosed by looking at the [[skin]]. Other diagnostic studies that can be used to [[diagnose]] dermatophytosis are matrix-assisted laser desorption ionization test and reflectance [[confocal microscopy]]. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
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Other diagnostic studies to confirm dermatophytosis may include: | Other diagnostic studies to confirm dermatophytosis may include: | ||
=== Matrix-assisted laser desorption | === Matrix-assisted laser desorption === | ||
* It is based on the detection of | * It is based on the detection of specific features of a [[Proteolysis|proteolytic]] degradation product which is a product of mycological infections or noninfectious diseases. | ||
* Dermatophytes are represented by proteolytic degradation products of native proteins. | * Dermatophytes are represented by [[Proteolysis|proteolytic]] [[degradation]] products of native [[proteins]]. | ||
* The peptide patterns of affected samples are compared with those of known samples containing peptide spectra from skin disorders stored in an already existing database. | * The [[peptide]] patterns of affected samples are compared with those of known samples containing [[peptide]] spectra from skin disorders stored in an already existing database. | ||
* It is a time efficient process, as it enables simultaneous identification of up to 64 dermatophyte strains, with results coming back within 24 hours. | * It is a time efficient process, as it enables simultaneous identification of up to 64 dermatophyte strains, with results coming back within 24 hours. | ||
=== Reflectance confocal microscopy === | === Reflectance confocal microscopy === | ||
* It | * It provides imaging of the [[Epidermis (skin)|epidermis]] and superficial [[dermis]] at a high resolution and can be used to detect [[cutaneous]] [[Fungus|fungi]] and [[parasitic]] infestations. | ||
* Branching fungal hyphae can be visualized over an erythematous, annular, scaly patch. | * Branching [[fungal]] [[hyphae]] can be visualized over an [[erythematous]], annular, [[Scaling skin|scaly]] patch. | ||
==References== | ==References== |
Revision as of 00:08, 27 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Most of the time, ringworm can be diagnosed by looking at the skin. Other diagnostic studies that can be used to diagnose dermatophytosis are matrix-assisted laser desorption ionization test and reflectance confocal microscopy.
Other Diagnostic Studies
Other diagnostic studies to confirm dermatophytosis may include:
Matrix-assisted laser desorption
- It is based on the detection of specific features of a proteolytic degradation product which is a product of mycological infections or noninfectious diseases.
- Dermatophytes are represented by proteolytic degradation products of native proteins.
- The peptide patterns of affected samples are compared with those of known samples containing peptide spectra from skin disorders stored in an already existing database.
- It is a time efficient process, as it enables simultaneous identification of up to 64 dermatophyte strains, with results coming back within 24 hours.
Reflectance confocal microscopy
- It provides imaging of the epidermis and superficial dermis at a high resolution and can be used to detect cutaneous fungi and parasitic infestations.
- Branching fungal hyphae can be visualized over an erythematous, annular, scaly patch.