Hirschsprung's disease natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death. Common complications include [[enterocolitis]], [[intestinal perforation]] and [[short bowel syndrome]]. | If left untreated, Hirschsprung's disease can lead to [[enterocolitis]] and even death. Common complications include: [[enterocolitis]], [[intestinal perforation]], and [[short bowel syndrome]]. Using appropriate surgical interventions, [[Mortality rate|mortality rate]] drops significantly. | ||
==Natural history== | ==Natural history== | ||
If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death. | If left untreated, Hirschsprung's disease can lead to [[enterocolitis]] and even death. | ||
==Complications== | ==Complications== | ||
* [[Inflammation]] and [[infection]] of the [[intestine]]s ([[enterocolitis]]) | |||
=== Possible complications of disease include: === | |||
* [[Inflammation]] and [[infection]] of the [[intestine]]s/[[colon]] ([[enterocolitis]]) <ref name="pmid6712314">{{cite journal |vauthors=Ikeda K, Goto S |title=Diagnosis and treatment of Hirschsprung's disease in Japan. An analysis of 1628 patients |journal=Ann. Surg. |volume=199 |issue=4 |pages=400–5 |year=1984 |pmid=6712314 |pmc=1353357 |doi= |url=}}</ref> | |||
* Intestinal perforation | * Intestinal perforation | ||
* [[Short bowel syndrome]], | * [[Short bowel syndrome]] (i.e., condition that can lead to [[malnourishment]] and [[dehydration]]) | ||
===Possible complications of surgery include=== | ===Possible complications of reconstructive surgery include:=== | ||
*Wound infection | *Wound infection | ||
*[[Anastomotic lesions| | *[[Anastomotic lesions|Anastomosis leakage]] | ||
*[[Intestinal obstruction]] | *[[Intestinal obstruction]] | ||
*[[Pelvic abscess]] | *[[Pelvic abscess]] | ||
*Chronic | *Chronic bowel obstruction symptoms | ||
*Chronic [[constipation]] or [[diarrhea]] | *Chronic [[constipation]] or [[diarrhea]] | ||
==Prognosis== | ==Prognosis== | ||
*Hirschsprung disease can lead to [[Mortality rate|mortality]] in up to 80% of cases. | *Hirschsprung's disease can lead to [[Mortality rate|mortality]] in up to 80% of cases. | ||
* | *Using appropriate surgical interventions, [[Mortality rate|mortality]] would drops to 30%. | ||
==References== | ==References== | ||
Revision as of 17:23, 27 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
If left untreated, Hirschsprung's disease can lead to enterocolitis and even death. Common complications include: enterocolitis, intestinal perforation, and short bowel syndrome. Using appropriate surgical interventions, mortality rate drops significantly.
Natural history
If left untreated, Hirschsprung's disease can lead to enterocolitis and even death.
Complications
Possible complications of disease include:
- Inflammation and infection of the intestines/colon (enterocolitis) [1]
- Intestinal perforation
- Short bowel syndrome (i.e., condition that can lead to malnourishment and dehydration)
Possible complications of reconstructive surgery include:
- Wound infection
- Anastomosis leakage
- Intestinal obstruction
- Pelvic abscess
- Chronic bowel obstruction symptoms
- Chronic constipation or diarrhea
Prognosis
- Hirschsprung's disease can lead to mortality in up to 80% of cases.
- Using appropriate surgical interventions, mortality would drops to 30%.