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* In the 18th century, Benjamin Franklin considered the causes and prevention of the common cold. | * In the 18th century, Benjamin Franklin considered the causes and prevention of the common cold. | ||
* After several years of research he concluded | * After several years of research, he concluded that "People often catch a cold from one another when shut up together in small close rooms, or coaches; and when sitting near and conversing, so as to breathe in each other's transpiration." | ||
* Although [[Virus|viruses]] had not yet been discovered, Franklin hypothesized that the common cold was passed between people through the air. | * Although [[Virus|viruses]] had not yet been discovered, Franklin hypothesized that the common cold was passed between people through the air. | ||
* He recommended exercise, bathing, and moderation in food and drink consumption to avoid the common cold.<ref>{{cite web | url = http://www.loc.gov/exhibits/treasures/franklin-scientist.html | title = Scientist and Inventor: Benjamin Franklin: In His Own Words... (AmericanTreasures of the Library of Congress)}}</ref> Franklin's theory on the [[Transmission (medicine)|transmission]] of the cold was confirmed | * He recommended exercise, bathing, and moderation in food and drink consumption to avoid the common cold.<ref>{{cite web | url = http://www.loc.gov/exhibits/treasures/franklin-scientist.html | title = Scientist and Inventor: Benjamin Franklin: In His Own Words... (AmericanTreasures of the Library of Congress)}}</ref> Franklin's theory on the [[Transmission (medicine)|transmission]] of the cold was confirmed about 150 years later.<ref name="pmid14795755">{{cite journal | author = Andrewes CH, Lovelock JE, Sommerville T | title = An experiment on the transmission of colds | journal = Lancet | volume = 1 | issue = 1 | pages = 25–7 | year = 1951 | pmid = 14795755 | doi = }}</ref> | ||
===Common Cold Unit=== | ===Common Cold Unit (CCU)=== | ||
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* In the United Kingdom, the [[Common Cold Unit]] was set up by the civilian [[Medical Research Council (UK)|Medical Research Council]] in 1946. The unit worked with volunteers who were infected with various viruses.<ref>{{cite book | title = Das Buch der verrückten Experimente (Broschiert) | author = Reto U. Schneider | year = 2004 | isbn = 344215393X | url = http://www.verrueckte-experimente.de/index_e.html}}</ref> | * In the United Kingdom, the [[Common Cold Unit]] (CCU) was set up by the civilian [[Medical Research Council (UK)|Medical Research Council]] in 1946. The unit worked with volunteers who were infected with various viruses.<ref>{{cite book | title = Das Buch der verrückten Experimente (Broschiert) | author = Reto U. Schneider | year = 2004 | isbn = 344215393X | url = http://www.verrueckte-experimente.de/index_e.html}}</ref> | ||
* The [[rhinovirus]] was discovered there in the | * The [[rhinovirus]] was discovered there in the CCU in the 1950s; scientists were able to culture the virus on a [[tissue culture]]. | ||
* In the 1970s, the CCU proved that using [[interferon]] in the incubation period is protective | * In the 1970s, the CCU proved that using [[interferon]] in the [[incubation period]] is protective against developing the infection, at some level. | ||
* In 1987, the unit completed its research on the [[zinc gluconate]] lozenges for [[prophylaxis]] against the [[rhinovirus]].<ref name="pmid3440773">{{cite journal| author=Al-Nakib W, Higgins PG, Barrow I, Batstone G, Tyrrell DA| title=Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges. | journal=J Antimicrob Chemother | year= 1987 | volume= 20 | issue= 6 | pages= 893-901 | pmid=3440773 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3440773 }} </ref> | * In 1987, the unit completed its' research on the [[zinc gluconate]] lozenges for [[prophylaxis]] against the [[rhinovirus]].<ref name="pmid3440773">{{cite journal| author=Al-Nakib W, Higgins PG, Barrow I, Batstone G, Tyrrell DA| title=Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges. | journal=J Antimicrob Chemother | year= 1987 | volume= 20 | issue= 6 | pages= 893-901 | pmid=3440773 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3440773 }} </ref> | ||
* In 1989, the unit was closed. | * In 1989, the unit was closed. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Common cold was first considered as a distinct diagnosis by Benjamin Franklin in the 18th century.
Historical Perspective
- In the 18th century, Benjamin Franklin considered the causes and prevention of the common cold.
- After several years of research, he concluded that "People often catch a cold from one another when shut up together in small close rooms, or coaches; and when sitting near and conversing, so as to breathe in each other's transpiration."
- Although viruses had not yet been discovered, Franklin hypothesized that the common cold was passed between people through the air.
- He recommended exercise, bathing, and moderation in food and drink consumption to avoid the common cold.[1] Franklin's theory on the transmission of the cold was confirmed about 150 years later.[2]
Common Cold Unit (CCU)
 |
- In the United Kingdom, the Common Cold Unit (CCU) was set up by the civilian Medical Research Council in 1946. The unit worked with volunteers who were infected with various viruses.[3]
- The rhinovirus was discovered there in the CCU in the 1950s; scientists were able to culture the virus on a tissue culture.
- In the 1970s, the CCU proved that using interferon in the incubation period is protective against developing the infection, at some level.
- In 1987, the unit completed its' research on the zinc gluconate lozenges for prophylaxis against the rhinovirus.[4]
- In 1989, the unit was closed.
References
- ↑ "Scientist and Inventor: Benjamin Franklin: In His Own Words... (AmericanTreasures of the Library of Congress)".
- ↑ Andrewes CH, Lovelock JE, Sommerville T (1951). "An experiment on the transmission of colds". Lancet. 1 (1): 25–7. PMID 14795755.
- ↑ Reto U. Schneider (2004). Das Buch der verrückten Experimente (Broschiert). ISBN 344215393X.
- ↑ Al-Nakib W, Higgins PG, Barrow I, Batstone G, Tyrrell DA (1987). "Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges". J Antimicrob Chemother. 20 (6): 893–901. PMID 3440773.