Heparin-induced thrombocytopenia causes: Difference between revisions
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==Overview== | ==Overview== | ||
[[Heparin-induced thrombocytopenia]] is | [[Heparin-induced thrombocytopenia]] is caused by a variety of factors. It is typically caused by unfractionated heparin (moreso than low-molecular weight heparin). Females are more likely to develop HIT. Patients undergoing cardiac surgery are more likely to develop HIT. | ||
==Causes== | ==Causes== |
Revision as of 20:44, 1 August 2017
Heparin-induced thrombocytopenia |
Differentiating Heparin-induced thrombocytopenia from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Aric C. Hall, M.D., [3] Shyam Patel [4]
Overview
Heparin-induced thrombocytopenia is caused by a variety of factors. It is typically caused by unfractionated heparin (moreso than low-molecular weight heparin). Females are more likely to develop HIT. Patients undergoing cardiac surgery are more likely to develop HIT.
Causes
- HIT is always caused by exogenous heparin or heparinoid exposure.
- Duration of heparin treatment: long duration, up to 2 weeks is associated with the greatest risk.[1]
- The type of heparin involved: unfractionated heparinUFH has a greater risk than low molecular weight heparin LMWH.[1]
- The type of patient: surgical patients are at higher risk than medical; cardiac surgical patients have the highest risk of all.[1]
- Gender: Females have a higher risk of HIT than males.
Reference
- ↑ 1.0 1.1 1.2 Lee GM, Arepally GM (2013). "Diagnosis and management of heparin-induced thrombocytopenia". Hematol Oncol Clin North Am. 27 (3): 541–63. doi:10.1016/j.hoc.2013.02.001. PMC 3668315. PMID 23714311.