Strongyloidiasis natural history, complications and prognosis: Difference between revisions
Aditya Ganti (talk | contribs) No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
{{CMG}} ; {{AE}} {{ADG}} | {{CMG}} ; {{AE}} {{ADG}} | ||
==Overview== | ==Overview== | ||
If strongyloidiasis is left untreated, the infection can disseminate and transform into | If strongyloidiasis is left untreated, the infection can disseminate and transform into hyperinfection syndrome, which has a mortality rate of 90%. Complications that can develop as a result of strongyloidiasis are disseminated strongyloidiasis (especially in patients with [[HIV]] or who are otherwise immunocompromised), [[eosinophilic pneumonia]], [[malnutrition]], and [[malabsorption]]. With appropriate treatment, people should make a full recovery. Treatment needs to be repeated often. [[Infections]] that are severe or widespread often have a poor outcome, especially in patients with a [[immunosuppression|suppressed immune system]].<ref name="pmid27213420">{{cite journal |vauthors=Beknazarova M, Whiley H, Ross K |title=Strongyloidiasis: A Disease of Socioeconomic Disadvantage |journal=Int J Environ Res Public Health |volume=13 |issue=5 |pages= |year=2016 |pmid=27213420 |pmc=4881142 |doi=10.3390/ijerph13050517 |url=}}</ref> | ||
==Natural history== | ==Natural history== | ||
If left untreated, the subclinical [[strongyloidiasis]] can disseminate and transform into [[Hyper infection syndrome| | If left untreated, the subclinical [[strongyloidiasis]] can disseminate and transform into [[Hyper infection syndrome|hyperinfection syndrome]], which has a [[mortality]] rate of 90%. | ||
==Complications== | ==Complications== | ||
| Line 15: | Line 15: | ||
==Prognosis== | ==Prognosis== | ||
With appropriate treatment, people should make a full recovery. Sometimes, treatment needs to be repeated. Infections that are severe or widespread often have a poor outcome, especially in | With appropriate treatment, people should make a full recovery. Sometimes, treatment needs to be repeated. Infections that are severe or widespread often have a poor outcome, especially in patients with a [[immunosuppression|suppressed immune system]]. [[Strongyloidiasis]] could be severe and life-threatening in specific groups including: | ||
*Those who use | *Those who use oral or [[intravenous]] [[steroids]], for example, in patients with [[asthma]], [[chronic obstructive pulmonary disease]] ([[COPD]]) exacerbations, [[lupus]], [[gout]], or in persons using [[steroids]] for [[immunosuppression]] or symptomatic relief | ||
*Those with [[HTLV-1]] infection | *Those with [[HTLV-1]] infection | ||
*Those with [[ | *Those with [[hematologic]] [[malignancies]] such as [[leukemia]] or [[lymphoma]] | ||
*[[Transplant|Transplant recipients]] | *[[Transplant|Transplant recipients]] | ||
Even with treatment, disseminated strongyloidiasis and hyperinfection syndrome have a mortality rate of 90%. | Even with treatment, disseminated strongyloidiasis and hyperinfection syndrome have a mortality rate of 90%. | ||
Revision as of 14:39, 3 August 2017
|
Strongyloidiasis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Strongyloidiasis natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Strongyloidiasis natural history, complications and prognosis |
|
FDA on Strongyloidiasis natural history, complications and prognosis |
|
CDC on Strongyloidiasis natural history, complications and prognosis |
|
Strongyloidiasis natural history, complications and prognosis in the news |
|
Blogs on Strongyloidiasis natural history, complications and prognosis |
|
Risk calculators and risk factors for Strongyloidiasis natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
If strongyloidiasis is left untreated, the infection can disseminate and transform into hyperinfection syndrome, which has a mortality rate of 90%. Complications that can develop as a result of strongyloidiasis are disseminated strongyloidiasis (especially in patients with HIV or who are otherwise immunocompromised), eosinophilic pneumonia, malnutrition, and malabsorption. With appropriate treatment, people should make a full recovery. Treatment needs to be repeated often. Infections that are severe or widespread often have a poor outcome, especially in patients with a suppressed immune system.[1]
Natural history
If left untreated, the subclinical strongyloidiasis can disseminate and transform into hyperinfection syndrome, which has a mortality rate of 90%.
Complications
Complications that can develop as a result of strongyloidiasis are:
- Disseminated strongyloidiasis, especially in patients with HIV or who are otherwise immunosuppressed
- Eosinophilic pneumonia
- Malnutrition due to problems absorbing nutrients from the gastrointestinal tract (malabsorption)
Prognosis
With appropriate treatment, people should make a full recovery. Sometimes, treatment needs to be repeated. Infections that are severe or widespread often have a poor outcome, especially in patients with a suppressed immune system. Strongyloidiasis could be severe and life-threatening in specific groups including:
- Those who use oral or intravenous steroids, for example, in patients with asthma, chronic obstructive pulmonary disease (COPD) exacerbations, lupus, gout, or in persons using steroids for immunosuppression or symptomatic relief
- Those with HTLV-1 infection
- Those with hematologic malignancies such as leukemia or lymphoma
- Transplant recipients
Even with treatment, disseminated strongyloidiasis and hyperinfection syndrome have a mortality rate of 90%.
References
- ↑ Beknazarova M, Whiley H, Ross K (2016). "Strongyloidiasis: A Disease of Socioeconomic Disadvantage". Int J Environ Res Public Health. 13 (5). doi:10.3390/ijerph13050517. PMC 4881142. PMID 27213420.