De Quervain's thyroiditis other diagnostic studies: Difference between revisions
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===Microscopic Pathology=== | ===Microscopic Pathology=== | ||
Microscopically | Microscopically, thyroid glands in de Quervain's thyroiditis may show:<ref name="pmid12608662">{{cite journal |vauthors=Kojima M, Nakamura S, Oyama T, Sugihara S, Sakata N, Masawa N |title=Cellular composition of subacute thyroiditis. an immunohistochemical study of six cases |journal=Pathol. Res. Pract. |volume=198 |issue=12 |pages=833–7 |year=2002 |pmid=12608662 |doi=10.1078/0344-0338-00344 |url=}}</ref> | ||
*Destruction of the follicular epithelium. | |||
*Loss of the follicular integrity. | |||
Revision as of 14:57, 3 August 2017
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De Quervain's thyroiditis Microchapters |
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Differentiating De Quervain's thyroiditis from other Diseases |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The histological analysis in de Quervain's thyroiditis may show inflammatory cell infiltration and hurthle cells. Fine needle aspiration cytology helps to differentiate between the benign and malignant nodules.[1]
Other Diagnostic Studies
Fine needle aspiration cytology
Fine needle aspiration is usually done under ultrasound guidance and the sample is sent for cytology. It helps to differentiate benign thyroid nodules from the malignant lesions.
Gross Pathology
- The gland is usually diffusely enlarged, firm, and slightly lobular. The capsule is intact, and the cut surface is light-tan and has a slight lobular pattern.
- At autopsy, significant subarachnoid hemorrhage from the ruptured berry aneurysm was documented. In addition, the thyroid gland was mildly enlarged and firm. On cut section, the tissue was slightly pale.
Microscopic Pathology
Microscopically, thyroid glands in de Quervain's thyroiditis may show:[2]
- Destruction of the follicular epithelium.
- Loss of the follicular integrity.
References
- ↑ "Thyroiditis — NEJM".
- ↑ Kojima M, Nakamura S, Oyama T, Sugihara S, Sakata N, Masawa N (2002). "Cellular composition of subacute thyroiditis. an immunohistochemical study of six cases". Pathol. Res. Pract. 198 (12): 833–7. doi:10.1078/0344-0338-00344. PMID 12608662.