Diabetic ketoacidosis causes: Difference between revisions

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Revision as of 15:15, 3 August 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Sugar which is the main source of energy for cells, need insulin to enter inside the cells. When the patient lack enough Insulin, sugar will not be able to enter inside the cell. This situation prompts the release of certain hormones that break down fat. The breakdown of fat produces ketones bodies. This process is triggered in the presence of any infection or illness.

Causes

The following are the causes of diabetic ketoacidosis (DKA):

Common Causes

Drugs:^[1]
- Antipsychotic agents: clozapine, olanzapine, risperidone
- Illicit drugs (cocaine and alcohol)
- Others: corticosteroids, glucagon, interferon, pentamidine, sympathomimetic agents, thiazide diuretics

Infections:
- Pneumonia
- Sepsis
- Urinary tract infection

Lack of insulin
Nonadherence to insulin treatment plans:
- Body image issues
- Financial problems
- Psychological factors

Unrecognized symptoms of new-onset diabetes mellitus

Physiological stressors:
- Acromegaly
- Thrombosis
- Cerebrovascular accident
- Cushing disease
- Hemochromatosis
- Myocardial infarction
- Pancreatitis
- Pregnancy
- Psychological stress
- Shock/hypovolemia
- Trauma

References

↑ Ramaswamy K, Kozma CM, Nasrallah H (2007). "Risk of diabetic ketoacidosis after exposure to risperidone or olanzapine". Drug Saf. 30 (7): 589–99. PMID 17604410.

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[pmid17604410-1] Ramaswamy K, Kozma CM, Nasrallah H (2007). "Risk of diabetic ketoacidosis after exposure to risperidone or olanzapine". Drug Saf. 30 (7): 589–99. PMID 17604410.

[1]

@@ Line 12: / Line 12: @@
 === Common Causes ===
-* Drugs:
+* Drugs:<ref name="pmid17604410">{{cite journal |vauthors=Ramaswamy K, Kozma CM, Nasrallah H |title=Risk of diabetic ketoacidosis after exposure to risperidone or olanzapine |journal=Drug Saf |volume=30 |issue=7 |pages=589–99 |year=2007 |pmid=17604410 |doi= |url=}}</ref>
 ** Antipsychotic agents: clozapine, olanzapine, risperidone
 ** Illicit drugs (cocaine and alcohol)