Euthyroid sick syndrome history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
Recent evidence has shown that subclinical hypothyroidism may have various consequences, such as [[hyperlipidemia]], increased risk of [[cardiovascular disease]] (even [[heart failure|heart failure)]], [[somatic]] and [[neuromuscular]] symptoms, [[infertility]], and other complications.<ref name="pmid8371604">{{cite journal |vauthors=O'Brien T, Dinneen SF, O'Brien PC, Palumbo PJ |title=Hyperlipidemia in patients with primary and secondary hypothyroidism |journal=Mayo Clin. Proc. |volume=68 |issue=9 |pages=860–6 |year=1993 |pmid=8371604 |doi= |url=}}</ref><ref name="pmid7605150">{{cite journal |vauthors=Diekman T, Lansberg PJ, Kastelein JJ, Wiersinga WM |title=Prevalence and correction of hypothyroidism in a large cohort of patients referred for dyslipidemia |journal=Arch. Intern. Med. |volume=155 |issue=14 |pages=1490–5 |year=1995 |pmid=7605150 |doi= |url=}}</ref><ref name="pmid18415684">{{cite journal |vauthors=Lania A, Persani L, Beck-Peccoz P |title=Central hypothyroidism |journal=Pituitary |volume=11 |issue=2 |pages=181–6 |year=2008 |pmid=18415684 |doi=10.1007/s11102-008-0122-6 |url=}}</ref> | |||
*The majority of patients with [disease name] are asymptomatic. | *The majority of patients with [disease name] are asymptomatic. | ||
OR | OR | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Patients of euthyroid sick syndrome present with serious illness and are febrile with hypermetabolism. In euthyroid sick syndrome the symptoms of the underlying condition may overlap with features of hypothyroidism. Generally it takes atleast 2-3 weeks for thyroid hormone levels to decline and symptoms of hypothyroidism takes even longer period for expression. [1]
The common symptoms and signs of clinical hypothyroidism are listed in the table below. The appearance of symptoms depends on the degree of hypothyroidism severity: [2][3][4][5]
| Symptoms | Constituitional | HEENT | Neuromuscular | Other findings |
|---|---|---|---|---|
| More common |
|
|
| |
| Less common |
|
|
|
Physical Examination
Laboratory Findings
Laboratory findings consistent with the diagnosis of euthyroid sick syndrome include
| Euthyroid sick syndrome | Laboratory test |
|---|---|
| Mild euthyroid sick syndrome |
|
| Moderate euthyroid sick syndrome |
|
| Severe euthyroid sick syndrome |
|
Imaging Findings
Other Diagnostic Studies
In euthyroid sick syndrome the thyroid gland appears normal. Therefore, there is no role of thyroid uptake scan in euthyroid sick syndrome.
History and Symptoms
Recent evidence has shown that subclinical hypothyroidism may have various consequences, such as hyperlipidemia, increased risk of cardiovascular disease (even heart failure), somatic and neuromuscular symptoms, infertility, and other complications.[6][7][8]
- The majority of patients with [disease name] are asymptomatic.
OR
- The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
- Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History
Patients with [disease name]] may have a positive history of:
- [history finding 1]
- [history finding 2]
- [history finding 3]
Common Symptoms
Common symptoms of [disease] include:
- [symptom 1]
- [symptom 2]
- [symptom 3]
Less Common Symptoms
Less common symptoms of [disease name] include
- [symptom 1]
- [symptom 2]
- [symptom 3]
References
- ↑ Fliers E, Bianco AC, Langouche L, Boelen A (2015). "Thyroid function in critically ill patients". Lancet Diabetes Endocrinol. 3 (10): 816–25. doi:10.1016/S2213-8587(15)00225-9. PMC 4979220. PMID 26071885.
- ↑ Carlé A, Pedersen IB, Knudsen N, Perrild H, Ovesen L, Laurberg P (2014). "Hypothyroid symptoms and the likelihood of overt thyroid failure: a population-based case-control study". Eur. J. Endocrinol. 171 (5): 593–602. doi:10.1530/EJE-14-0481. PMID 25305308.
- ↑ Diaz A, Lipman Diaz EG (2014). "Hypothyroidism". Pediatr Rev. 35 (8): 336–47, quiz 348–9. doi:10.1542/pir.35-8-336. PMID 25086165.
- ↑ Samuels MH (2014). "Psychiatric and cognitive manifestations of hypothyroidism". Curr Opin Endocrinol Diabetes Obes. 21 (5): 377–83. doi:10.1097/MED.0000000000000089. PMC 4264616. PMID 25122491.
- ↑ McDermott MT (2009). "In the clinic. Hypothyroidism". Ann. Intern. Med. 151 (11): ITC61. doi:10.7326/0003-4819-151-11-200912010-01006. PMID 19949140.
- ↑ O'Brien T, Dinneen SF, O'Brien PC, Palumbo PJ (1993). "Hyperlipidemia in patients with primary and secondary hypothyroidism". Mayo Clin. Proc. 68 (9): 860–6. PMID 8371604.
- ↑ Diekman T, Lansberg PJ, Kastelein JJ, Wiersinga WM (1995). "Prevalence and correction of hypothyroidism in a large cohort of patients referred for dyslipidemia". Arch. Intern. Med. 155 (14): 1490–5. PMID 7605150.
- ↑ Lania A, Persani L, Beck-Peccoz P (2008). "Central hypothyroidism". Pituitary. 11 (2): 181–6. doi:10.1007/s11102-008-0122-6. PMID 18415684.