Lyme disease secondary prevention: Difference between revisions
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*The [[secondary prevention]] of Lyme disease may include post exposure [[prophylaxis]] with [[doxycycline]] in selected cases meeting criteria for [[chemoprophylaxis]]. | *The [[secondary prevention]] of Lyme disease may include post exposure [[prophylaxis]] with [[doxycycline]] in selected cases meeting criteria for [[chemoprophylaxis]]. | ||
*The criteria for [[chemoprophylaxis]] includes:<ref name="pmid17029130">{{cite journal|year=2006|title=The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America.|url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17029130|journal=Clin Infect Dis|volume=43|issue=9|pages=1089-134|doi=10.1086/508667|pmc=|pmid=17029130|author=Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS et al.}}</ref> | *The criteria for [[chemoprophylaxis]] includes:<ref name="pmid17029130">{{cite journal|year=2006|title=The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America.|url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17029130|journal=Clin Infect Dis|volume=43|issue=9|pages=1089-134|doi=10.1086/508667|pmc=|pmid=17029130|author=Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS et al.}}</ref> | ||
* A single dose of [[doxycycline]] '''(avoid in [[pregnancy]] and children <8 years)''' may be offered to adults (200mg) and children (4mg/kg, maximum 200mg) if all of the criteria are fulfilled: | * A single dose of [[doxycycline]] '''(avoid in [[pregnancy]] and children <8 years)''' may be offered to adults (200mg) and children (4mg/kg, maximum 200mg) if all of the following criteria are fulfilled: | ||
** The [[tick]] is identified as ''[[I. scapularis]]'' (adult or nymph) | ** The [[tick]] is identified as ''[[I. scapularis]]'' (adult or nymph) | ||
** The [[tick]] has been attached for > 36 hours. Attachment time is estimated by the degree of engorgement of the [[tick]] with blood or approximating the time of exposure to the [[tick]]. | ** The [[tick]] has been attached for > 36 hours. Attachment time is estimated by the degree of engorgement of the [[tick]] with blood or approximating the time of exposure to the [[tick]]. | ||
** Prophylaxis should be stated within 72 hours of tick removal. | ** Prophylaxis should be stated within 72 hours of tick removal. | ||
** Local [[infection]] rate of [[ | ** Local [[infection]] rate of [[ticks]] with ''[[Borrelia burgdorferi|B. burgdorferi]]'' is > 20%. | ||
** There is no contraindication to use of [[doxycycline]]. | ** There is no contraindication to use of [[doxycycline]]. | ||
==References== | ==References== |
Revision as of 19:09, 7 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]
Overview
The secondary prevention of Lyme disease may include post exposure prophylaxis with doxycycline in select cases meeting criteria for chemoprophylaxis.
Secondary prevention
- After a tick bite, routine use of antibiotic prophylaxis is not recommended.
- The secondary prevention of Lyme disease may include post exposure prophylaxis with doxycycline in selected cases meeting criteria for chemoprophylaxis.
- The criteria for chemoprophylaxis includes:[1]
- A single dose of doxycycline (avoid in pregnancy and children <8 years) may be offered to adults (200mg) and children (4mg/kg, maximum 200mg) if all of the following criteria are fulfilled:
- The tick is identified as I. scapularis (adult or nymph)
- The tick has been attached for > 36 hours. Attachment time is estimated by the degree of engorgement of the tick with blood or approximating the time of exposure to the tick.
- Prophylaxis should be stated within 72 hours of tick removal.
- Local infection rate of ticks with B. burgdorferi is > 20%.
- There is no contraindication to use of doxycycline.
References
- ↑ Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS; et al. (2006). "The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America". Clin Infect Dis. 43 (9): 1089–134. doi:10.1086/508667. PMID 17029130.