Thyroid nodule differential diagnosis: Difference between revisions
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! rowspan="2" |Biopsy result | ! rowspan="2" |Biopsy result | ||
if indicated | if indicated | ||
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!FNA finding | !FNA finding | ||
!Associated mutation | !Associated mutation | ||
!special consideration | |||
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|Benign | |Benign | ||
|Colloid adenoma | |Colloid adenoma | ||
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|Hashimoto's thyroiditis | |Hashimoto's thyroiditis | ||
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|Cysts nodules | |Cysts nodules | ||
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* PAX8-PPAR gamma 1 | * PAX8-PPAR gamma 1 | ||
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* ''RAS'' mutations | * ''RAS'' mutations | ||
* PAX8-PPAR gamma 1 | * PAX8-PPAR gamma 1 | ||
|Most common thyroid cancer in iodine deficient areas | |||
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|Oxyphilic (Hürthle cell) type carcinoma | |Oxyphilic (Hürthle cell) type carcinoma | ||
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|Noninvasive follicular thyroid neoplasm | |Noninvasive follicular thyroid neoplasm | ||
with papillary-like nuclear features | with papillary-like nuclear features | ||
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|Medullary carcinoma | |Medullary carcinoma | ||
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|↑ | |↑ | ||
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|Primary thyroid lymphoma | |Primary thyroid lymphoma | ||
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|Metastatic carcinoma | |Metastatic carcinoma | ||
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Revision as of 18:27, 9 August 2017
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Thyroid nodule Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Thyroid nodule differential diagnosis On the Web |
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American Roentgen Ray Society Images of Thyroid nodule differential diagnosis |
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Risk calculators and risk factors for Thyroid nodule differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]
Overview
Thyroid nodule differential diagnosis
In rare cases, a thyroid nodule may reflect one of the hereditary nonmedullary thyroid cancer syndromes such as familial adenomatous polyposis, Werner’s syndrome, Carney complex type 1, or Gardner’s syndrome
| Nodule property | Spread | Sudden growth
of neck mass |
Laboratory | Thyroid scintigraphy | Biopsy result
if indicated |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fixed | Mobile | Painful | LN | Vessle | Metastasis | TSH | FT4/T3 | Hot | Cold | US finding | FNA finding | Associated mutation | special consideration | ||||
| Benign | Colloid adenoma | ||||||||||||||||
| Hashimoto's thyroiditis | |||||||||||||||||
| Cysts nodules | |||||||||||||||||
| Follicular adenomas | ↑↑↑ |
|
|||||||||||||||
| Hyperplastic nodules | ↑↑↑ | ||||||||||||||||
| Macrofollicular adenomas | ↑↑ | ||||||||||||||||
| Microfollicular or cellular adenomas | ↑↑ | ||||||||||||||||
| Hürthle cell adenomas | ↑↓ | ||||||||||||||||
| Malignant | Papillary carcinoma | ↑↑↑ | |||||||||||||||
| Follicular carcinoma | ↑↑↑ | Bone
Lung |
↑↓ | FLUS |
|
|
Most common thyroid cancer in iodine deficient areas | ||||||||||
| Oxyphilic (Hürthle cell) type carcinoma | |||||||||||||||||
| Noninvasive follicular thyroid neoplasm
with papillary-like nuclear features |
|||||||||||||||||
| Medullary carcinoma | |||||||||||||||||
| Anaplastic carcinoma | ↑ | ||||||||||||||||
| Primary thyroid lymphoma | |||||||||||||||||
| Metastatic carcinoma | |||||||||||||||||