Psittacosis medical therapy: Difference between revisions
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::* 1.2 '''Pediatric''' | ::* 1.2 '''Pediatric''' | ||
:::* 1.2.1 '''Mild infection, Infants > 3 months''' | :::* 1.2.1 '''Mild infection, Infants > 3 months''' | ||
::::* Preferred regimen: [[Azithromycin]] 10 mg/kg PO qd on day 1 {{then}} 5 mg/kg PO q24h for 4 days (maximum | ::::* Preferred regimen: [[Azithromycin]] 10 mg/kg PO qd on day 1 {{then}} 5 mg/kg PO q24h for 4 days (maximum 500 mg for 1st dose, 250 mg for subsequent doses) | ||
:::* 1.2.2 '''Moderate-severe infection, Infants | :::* 1.2.2 '''Moderate-severe infection, Infants > 3 months''' | ||
::::* Preferred regimen: [[Azithromycin]] 10 mg/kg IV q24h for 2 days {{then}} 5 mg/kg PO qd for 3 days (maximum | ::::* Preferred regimen: [[Azithromycin]] 10 mg/kg IV q24h for 2 days {{then}} 5 mg/kg PO qd for 3 days (maximum 500 mg/dose IV or 250 mg/dose PO) | ||
::* 1.3 '''Pregnant Patients''' | ::* 1.3 '''Pregnant Patients''' | ||
:::* Preferred regimen: [[Azithromycin]] 500 mg PO on day 1 {{then}} | :::* Preferred regimen: [[Azithromycin]] 500 mg PO on day 1 {{then}} 250 mg qd on days 2-5 {{or}} 500 mg IV as a single dose for at least 2 days, followed by 500 mg PO qd for 7-10 days | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 18:46, 9 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Psittacosis is treated with tetracyclines. Remission of symptoms usually is evident within 48-72 hours. However, relapse can occur, and treatment must continue for at least 10-14 days after fever abates. For pregnant patients or infants, the preferred treatment is azithromycin because tetracyclines are contraindicated.
Medical Therapy
Antimicrobial Regimen
- 1. Psittacosis[1]
- 1.1 Adult
- Preferred regimen (1): Doxycycline 100 mg PO bid for 10-21 days
- Preferred regimen (2): Tetracycline 500 mg PO qid for 10-21 days
- Alternative regimen: Minocycline
- 1.2 Pediatric
- 1.2.1 Mild infection, Infants > 3 months
- Preferred regimen: Azithromycin 10 mg/kg PO qd on day 1 THEN 5 mg/kg PO q24h for 4 days (maximum 500 mg for 1st dose, 250 mg for subsequent doses)
- 1.2.2 Moderate-severe infection, Infants > 3 months
- Preferred regimen: Azithromycin 10 mg/kg IV q24h for 2 days THEN 5 mg/kg PO qd for 3 days (maximum 500 mg/dose IV or 250 mg/dose PO)
- 1.3 Pregnant Patients
- Preferred regimen: Azithromycin 500 mg PO on day 1 THEN 250 mg qd on days 2-5 OR 500 mg IV as a single dose for at least 2 days, followed by 500 mg PO qd for 7-10 days
References
- ↑ Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455748013.