Pheochromocytoma other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
*[[Clonidine#Clonidine suppression test|Clonidine suppression test]] may be used to diagnose pheochromocytoma.<ref name="pmid26335433">{{cite journal| author=Goupil R, Fountoulakis S, Gordon RD, Stowasser M| title=Urinary clonidine suppression testing for the diagnosis of pheochromocytoma. | journal=J Hypertens | year= 2015 | volume= 33 | issue= 11 | pages= 2286-93 | pmid=26335433 | doi=10.1097/HJH.0000000000000705 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26335433 }}</ref> | *[[Clonidine#Clonidine suppression test|Clonidine suppression test]] may be used to diagnose pheochromocytoma.<ref name="pmid26335433">{{cite journal| author=Goupil R, Fountoulakis S, Gordon RD, Stowasser M| title=Urinary clonidine suppression testing for the diagnosis of pheochromocytoma. | journal=J Hypertens | year= 2015 | volume= 33 | issue= 11 | pages= 2286-93 | pmid=26335433 | doi=10.1097/HJH.0000000000000705 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26335433 }}</ref> | ||
*[[Clonidine]] is a centrally-acting [[Alpha-2 receptor|alpha-2 agonist]] used to treat high blood pressure. | *[[Clonidine]] is a centrally-acting [[Alpha-2 receptor|alpha-2 agonist]] used to treat high [[blood pressure]]. | ||
*[[Clonidine]] mimics catecholamines in the brain and reduces the activity of the [[sympathetic nerves]] controlling the adrenal medulla. | *[[Clonidine]] mimics [[catecholamines]] in the [[brain]] and reduces the activity of the [[sympathetic nerves]] controlling the [[adrenal medulla]]. | ||
*Healthy [[adrenal medulla]] will respond to the [[ | *Healthy [[adrenal medulla]] will respond to the [[clonidine]] suppression test by reducing [[catecholamine]] production. | ||
*Lack of a response is evidence of pheochromocytoma. | *Lack of a response (no reduction in [[catecholamine]] levels after test) is evidence of pheochromocytoma. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
Revision as of 14:55, 16 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2] Mohammed Abdelwahed M.D[3]
Overview
Clonidine suppression test may be used in the diagnosis of pheochromocytoma.
Other Diagnostic Studies
- Clonidine suppression test may be used to diagnose pheochromocytoma.[1]
- Clonidine is a centrally-acting alpha-2 agonist used to treat high blood pressure.
- Clonidine mimics catecholamines in the brain and reduces the activity of the sympathetic nerves controlling the adrenal medulla.
- Healthy adrenal medulla will respond to the clonidine suppression test by reducing catecholamine production.
- Lack of a response (no reduction in catecholamine levels after test) is evidence of pheochromocytoma.
References
- ↑ Goupil R, Fountoulakis S, Gordon RD, Stowasser M (2015). "Urinary clonidine suppression testing for the diagnosis of pheochromocytoma". J Hypertens. 33 (11): 2286–93. doi:10.1097/HJH.0000000000000705. PMID 26335433.