Diabetic ketoacidosis classification: Difference between revisions
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=== Classification based on severity === | === Classification based on severity === | ||
Diabetic ketoacidosis (DKA) may be classified according to severity into the following types:<ref name="urlDiabetic Ketoacidosis - Endotext - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK279146/ |title=Diabetic Ketoacidosis - Endotext - NCBI Bookshelf |format= |work= |accessdate=}}</ref> | Diabetic ketoacidosis (DKA) may be classified according to severity into the following types:<ref name="urlDiabetic Ketoacidosis - Endotext - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK279146/ |title=Diabetic Ketoacidosis - Endotext - NCBI Bookshelf |format= |work= |accessdate=}}</ref><ref name="urlDiabetic Ketoacidosis - American Family Physician">{{cite web |url=http://www.aafp.org/afp/2005/0501/p1705.html |title=Diabetic Ketoacidosis - American Family Physician |format= |work= |accessdate=}}</ref> | ||
* Mild DKA | * Mild DKA | ||
* Moderate DKA | * Moderate DKA | ||
* Severe DKA | * Severe DKA | ||
{| class="wikitable" | {| class="wikitable" | ||
! colspan="1" rowspan="2" |VARIABLE | ! colspan="1" rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" + |VARIABLE | ||
! colspan="3" rowspan="1" |DIABETIC KETOACIDOSIS | ! colspan="3" rowspan="1" align="center" style="background:#4479BA; color: #FFFFFF;" + |DIABETIC KETOACIDOSIS | ||
|- | |- | ||
! colspan="1" rowspan="1" |MILD (SERUM GLUCOSE > 250 MG PER DL [13.88 MMOL PER L]) | ! colspan="1" rowspan="1" align="center" style="background:#4479BA; color: #FFFFFF;" + |MILD (SERUM GLUCOSE > 250 MG PER DL [13.88 MMOL PER L]) | ||
! colspan="1" rowspan="1" |MODERATE (SERUM GLUCOSE > 250 MG PER DL) | ! colspan="1" rowspan="1" align="center" style="background:#4479BA; color: #FFFFFF;" + |MODERATE (SERUM GLUCOSE > 250 MG PER DL) | ||
! colspan="1" rowspan="1" |SEVERE (SERUM GLUCOSE > 250 MG PER DL) | ! colspan="1" rowspan="1" align="center" style="background:#4479BA; color: #FFFFFF;" + |SEVERE (SERUM GLUCOSE > 250 MG PER DL) | ||
|- | |- | ||
| colspan="1" rowspan="1" |'''[[Anion gap]]''' | | colspan="1" rowspan="1" | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Anion gap]]''' | ||
| colspan="1" rowspan="1" |> 10 mEq per L (10 mmol per L) | | colspan="1" rowspan="1" |> 10 mEq per L (10 mmol per L) | ||
| colspan="1" rowspan="1" |> 12 mEq per L (12 mmol per L) | | colspan="1" rowspan="1" |> 12 mEq per L (12 mmol per L) | ||
| colspan="1" rowspan="1" |> 12 mEq per L (12 mmol per L) | | colspan="1" rowspan="1" |> 12 mEq per L (12 mmol per L) | ||
|- | |- | ||
| colspan="1" rowspan="1" |'''[[Arterial]] [[pH]]''' | | colspan="1" rowspan="1" | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Arterial]] [[pH]]''' | ||
| colspan="1" rowspan="1" |7.24 to 7.30 | | colspan="1" rowspan="1" |7.24 to 7.30 | ||
| colspan="1" rowspan="1" |7.00 to < 7.24 | | colspan="1" rowspan="1" |7.00 to < 7.24 | ||
| colspan="1" rowspan="1" |< 7.00 | | colspan="1" rowspan="1" |< 7.00 | ||
|- | |- | ||
| colspan="1" rowspan="1" |'''[[Osmolarity|Effective serum osmolality]]''' | | colspan="1" rowspan="1" | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Osmolarity|Effective serum osmolality]]''' | ||
| colspan="1" rowspan="1" |Variable | | colspan="1" rowspan="1" |Variable | ||
| colspan="1" rowspan="1" |Variable | | colspan="1" rowspan="1" |Variable | ||
| colspan="1" rowspan="1" |Variable | | colspan="1" rowspan="1" |Variable | ||
|- | |- | ||
| colspan="1" rowspan="1" |'''[[Mental status]]''' | | colspan="1" rowspan="1" | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Mental status]]''' | ||
| colspan="1" rowspan="1" |Alert | | colspan="1" rowspan="1" |Alert | ||
| colspan="1" rowspan="1" |Alert/drowsy | | colspan="1" rowspan="1" |Alert/drowsy | ||
| colspan="1" rowspan="1" |Stupor/coma | | colspan="1" rowspan="1" |Stupor/coma | ||
|- | |- | ||
| colspan="1" rowspan="1" |'''[[Serum]] [[bicarbonate]]''' | | colspan="1" rowspan="1" | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Serum]] [[bicarbonate]]''' | ||
| colspan="1" rowspan="1" |15 to 18 mEq per L (15 to 18 mmol per L) | | colspan="1" rowspan="1" |15 to 18 mEq per L (15 to 18 mmol per L) | ||
| colspan="1" rowspan="1" |10 to < 15 mEq per L (10 to < 15 mmol per L) | | colspan="1" rowspan="1" |10 to < 15 mEq per L (10 to < 15 mmol per L) | ||
| colspan="1" rowspan="1" |< 10 mEq per L (10 mmol per L) | | colspan="1" rowspan="1" |< 10 mEq per L (10 mmol per L) | ||
|- | |- | ||
| colspan="1" rowspan="1" |'''[[Serum]] [[ketones]]''' | | colspan="1" rowspan="1" | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Serum]] [[ketones]]''' | ||
| colspan="1" rowspan="1" |Positive | | colspan="1" rowspan="1" |Positive | ||
| colspan="1" rowspan="1" |Positive | | colspan="1" rowspan="1" |Positive |
Revision as of 15:28, 22 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
Diabetic ketoacidosis (DKA) may be classified according to severity into mild, moderate and severe DKA. The classification takes into account various parameters for example, arterial pH, anion gap, effective serum osmolarity, mental status, serum bicarbonate levels and serum ketone levels. Classification of DKA has important implications in the management of the disease.
Classification
Classification based on severity
Diabetic ketoacidosis (DKA) may be classified according to severity into the following types:[1][2]
- Mild DKA
- Moderate DKA
- Severe DKA
VARIABLE | DIABETIC KETOACIDOSIS | ||
---|---|---|---|
MILD (SERUM GLUCOSE > 250 MG PER DL [13.88 MMOL PER L]) | MODERATE (SERUM GLUCOSE > 250 MG PER DL) | SEVERE (SERUM GLUCOSE > 250 MG PER DL) | |
style="background: #DCDCDC; padding: 5px; text-align: center;" |Anion gap | > 10 mEq per L (10 mmol per L) | > 12 mEq per L (12 mmol per L) | > 12 mEq per L (12 mmol per L) |
style="background: #DCDCDC; padding: 5px; text-align: center;" |Arterial pH | 7.24 to 7.30 | 7.00 to < 7.24 | < 7.00 |
style="background: #DCDCDC; padding: 5px; text-align: center;" |Effective serum osmolality | Variable | Variable | Variable |
style="background: #DCDCDC; padding: 5px; text-align: center;" |Mental status | Alert | Alert/drowsy | Stupor/coma |
style="background: #DCDCDC; padding: 5px; text-align: center;" |Serum bicarbonate | 15 to 18 mEq per L (15 to 18 mmol per L) | 10 to < 15 mEq per L (10 to < 15 mmol per L) | < 10 mEq per L (10 mmol per L) |
style="background: #DCDCDC; padding: 5px; text-align: center;" |Serum ketones | Positive | Positive | Positive |