De Quervain's thyroiditis other diagnostic studies: Difference between revisions
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Image:Subacute thyroiditis - intermed mag.jpg|center|thumb|250px|'''De Quervain's thyroiditis; Granuloma''' (By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=18491382) | Image:Subacute thyroiditis - intermed mag.jpg|center|thumb|250px|'''De Quervain's thyroiditis; Granuloma'''<SMALL><SMALL> (By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=18491382)</SMALL></SMALL> | ||
Image:Subacute thyroiditis - high mag.jpg|center|thumb|250px|'''De Quervain's thyroiditis; Granuloma''' (By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=18491421) | Image:Subacute thyroiditis - high mag.jpg|center|thumb|250px|'''De Quervain's thyroiditis; Granuloma'''<SMALL><SMALL> (By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=18491421)</SMALL></SMALL> | ||
Image:Subacute thyroiditis - very high mag.jpg|center|thumb|250px|'''De Quervain's thyroiditis; Granuloma''' (By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=18491421) | Image:Subacute thyroiditis - very high mag.jpg|center|thumb|250px|'''De Quervain's thyroiditis; Granuloma'''<SMALL><SMALL> (By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=18491421)</SMALL></SMALL> | ||
Image:Subacute-de-quervains-thyroiditis (3).jpg|center|thumb|250px|'''De Quervain's thyroiditis; FNA smear'''; Inflammatory rich smear with giant cells and probable granulomata. (Case courtesy of Dr Andrew Ryan, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/17052">rID: 17052</a>)]]) | Image:Subacute-de-quervains-thyroiditis (3).jpg|center|thumb|250px|'''De Quervain's thyroiditis; FNA smear'''; Inflammatory rich smear with giant cells and probable granulomata.<SMALL><SMALL> (Case courtesy of Dr Andrew Ryan, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/17052">rID: 17052</a>)]])</SMALL></SMALL> | ||
Image:Subacute-de-quervains-thyroiditis (4).jpg|center|thumb|250px|'''De Quervain's thyroiditis; FNA smear'''; Cluster of epithelioid histiocytes with associated inflammatory cells and debris and group of benign follicular epithelial cells. (Case courtesy of Dr Andrew Ryan, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/17052">rID: 17052</a>) | Image:Subacute-de-quervains-thyroiditis (4).jpg|center|thumb|250px|'''De Quervain's thyroiditis; FNA smear'''; Cluster of epithelioid histiocytes with associated inflammatory cells and debris and group of benign follicular epithelial cells.<SMALL><SMALL> (Case courtesy of Dr Andrew Ryan, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/17052">rID: 17052</a>)</SMALL></SMALL> | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 03:15, 23 August 2017
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De Quervain's thyroiditis Microchapters |
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Differentiating De Quervain's thyroiditis from other Diseases |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The histological analysis in de Quervain's thyroiditis may show the destruction of the follicular epithelium, loss of the follicular integrity, and infiltration of inflammatory cells. Fine needle aspiration cytology helps to differentiate between the benign and malignant nodules.
Other Diagnostic Studies
Fine needle aspiration cytology
Fine needle aspiration is usually done under ultrasound guidance and the sample is sent for cytology. It helps to differentiate benign thyroid nodules from the malignant lesions.[1][2]
Microscopic Pathology
Microscopic findings suggesting de Quervain's thyroiditis are as followings:[3]
- Granuloma comprises of colloid, small lymphocytes, neutrophils, and macrophages with or without epithelioid features
- Destruction of the follicular epithelium
- Loss of the follicular integrity
- Patchy distribution of non-caseous granulomas
Gallery
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De Quervain's thyroiditis; Granuloma (By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=18491382) -
De Quervain's thyroiditis; Granuloma (By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=18491421) -
De Quervain's thyroiditis; Granuloma (By Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=18491421) -
![De Quervain's thyroiditis; FNA smear; Inflammatory rich smear with giant cells and probable granulomata. (Case courtesy of Dr Andrew Ryan, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/17052">rID: 17052</a>)]])](/images/1/1c/Subacute-de-quervains-thyroiditis_%283%29.jpg)
De Quervain's thyroiditis; FNA smear; Inflammatory rich smear with giant cells and probable granulomata. (Case courtesy of Dr Andrew Ryan, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/17052">rID: 17052</a>)]]) -
De Quervain's thyroiditis; FNA smear; Cluster of epithelioid histiocytes with associated inflammatory cells and debris and group of benign follicular epithelial cells. (Case courtesy of Dr Andrew Ryan, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/17052">rID: 17052</a>)
![De Quervain's thyroiditis; FNA smear; Inflammatory rich smear with giant cells and probable granulomata. (Case courtesy of Dr Andrew Ryan, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/17052">rID: 17052</a>)]])](/index.php/File:Subacute-de-quervains-thyroiditis_(3).jpg)
.jpg)
References
- ↑ "Thyroiditis — NEJM".
- ↑ Fatourechi V, Aniszewski JP, Fatourechi GZ, Atkinson EJ, Jacobsen SJ (2003). "Clinical features and outcome of subacute thyroiditis in an incidence cohort: Olmsted County, Minnesota, study". J. Clin. Endocrinol. Metab. 88 (5): 2100–5. doi:10.1210/jc.2002-021799. PMID 12727961.
- ↑ Kojima M, Nakamura S, Oyama T, Sugihara S, Sakata N, Masawa N (2002). "Cellular composition of subacute thyroiditis. an immunohistochemical study of six cases". Pathol. Res. Pract. 198 (12): 833–7. doi:10.1078/0344-0338-00344. PMID 12608662.