Hashimoto's thyroiditis causes: Difference between revisions
Jump to navigation
Jump to search
| Line 14: | Line 14: | ||
===Less common cause=== | ===Less common cause=== | ||
*[[Immunomodulatory]] drugs (e.g, [[interferon-alpha]] | *[[Immunomodulatory]] drugs (e.g, [[interferon-alpha]]) | ||
*[[Monoclonal antibodies]] that block [[CTLA-4]] | *[[Monoclonal antibodies]] that block [[CTLA-4]] | ||
*[[Cancer]] vaccines | *[[Cancer]] vaccines | ||
Revision as of 16:26, 31 August 2017
|
Hashimoto's thyroiditis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Hashimoto's thyroiditis causes On the Web |
|
American Roentgen Ray Society Images of Hashimoto's thyroiditis causes |
|
Risk calculators and risk factors for Hashimoto's thyroiditis causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
Hashimoto's thyroiditis may be caused by T cells and B cells auto activation, genetic factors, and autoimmune antibodies against thyrotropin receptors.
Causes
Hashimoto's thyroiditis usually caused by:[1]
Common causes
- Autoantibodies against thyroid peroxidase and thyroglobulin.
- Abnormalities in the suppressor T cells and regulatory T cells.
- HLA-B* 46:01, HLA-A* 02:07 and HLA-DRB4 involvement.
Less common cause
- Immunomodulatory drugs (e.g, interferon-alpha)
- Monoclonal antibodies that block CTLA-4
- Cancer vaccines
- Micro RNA involvement
- Polyglandular Syndrome
For the factors involved in the development of Hashimoto's thyroiditis, please click here.
References
- ↑ Ajjan RA, Weetman AP (2015). "The Pathogenesis of Hashimoto's Thyroiditis: Further Developments in our Understanding". Horm. Metab. Res. 47 (10): 702–10. doi:10.1055/s-0035-1548832. PMID 26361257.