Sheehan's syndrome causes: Difference between revisions
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==Overview== | ==Overview== | ||
Common causes of Sheehan's syndrome | Common causes of Sheehan's syndrome are including massive [[hemorrhage]], [[hypotension]] during [[pregnancy]], vascular compression, and vascular occlusion ([[thrombosis]], [[Disseminated intravascular coagulation|DIC]]). Less common causes are including vascular insufficiency due to [[Coronary artery bypass surgery|coronary artery bypass grafting (CABG)]] in older patients and [[Snake bite (Viperidae)|snake bites]] (Russell's viper bites). | ||
==Causes== | ==Causes== | ||
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===Common Causes=== | ===Common Causes=== | ||
Sheehan's syndrome may be caused by the followings: | |||
*Massive [[hemorrhage]] during and after pregnancy | *Massive [[hemorrhage]] during and after pregnancy | ||
*Vascular compression due to enlarged [[pituitary gland]] or small and rigid [[sella]] | *Vascular compression due to enlarged [[pituitary gland]] or small and rigid [[sella]] | ||
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===Less Common Causes=== | ===Less Common Causes=== | ||
Less common causes of | Less common causes of Sheehan's syndrome are including: | ||
*[[Vascular insufficiency|Vascular insufficienc]]<nowiki/>y due to [[Coronary artery bypass surgery|CABG]] in older patients<ref name="pmid9522796">{{cite journal |vauthors=Davies JS, Scanlon MF |title=Hypopituitarism after coronary artery bypass grafting |journal=BMJ |volume=316 |issue=7132 |pages=682–4 |year=1998 |pmid=9522796 |pmc=1112681 |doi= |url=}}</ref> | *[[Vascular insufficiency|Vascular insufficienc]]<nowiki/>y due to [[Coronary artery bypass surgery|CABG]] in older patients<ref name="pmid9522796">{{cite journal |vauthors=Davies JS, Scanlon MF |title=Hypopituitarism after coronary artery bypass grafting |journal=BMJ |volume=316 |issue=7132 |pages=682–4 |year=1998 |pmid=9522796 |pmc=1112681 |doi= |url=}}</ref> | ||
*[[Snake bite (Viperidae)|Snake bites]] (Russell's [[viper]] bites) | *[[Snake bite (Viperidae)|Snake bites]] (Russell's [[viper]] bites)<ref name="pmid21115460">{{cite journal |vauthors=Antonypillai CN, Wass JA, Warrell DA, Rajaratnam HN |title=Hypopituitarism following envenoming by Russell's vipers (Daboia siamensis and D. russelii) resembling Sheehan's syndrome: first case report from Sri Lanka, a review of the literature and recommendations for endocrine management |journal=QJM |volume=104 |issue=2 |pages=97–108 |year=2011 |pmid=21115460 |doi=10.1093/qjmed/hcq214 |url=}}</ref> | ||
===Genetic Causes=== | ===Genetic Causes=== | ||
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{| style="width:80%; height:100px" border="1" | {| style="width:80%; height:100px" border="1" | ||
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular''' | | style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular''' | ||
| style="width:75%" bgcolor="Beige" ; border="1" | Hypotension , | | style="width:75%" bgcolor="Beige" ; border="1" | [[Hypotension]], Vascular compression, [[Hemorrhage]] | ||
|- | |- | ||
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning''' | | bgcolor="LightSteelBlue" | '''Chemical/Poisoning''' | ||
| bgcolor="Beige" | Snake bites | | bgcolor="Beige" | [[Snake bite|Snake bites]] | ||
|- | |- | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| Line 67: | Line 67: | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
| bgcolor="Beige" | Thrombosis, DIC | | bgcolor="Beige" | [[Thrombosis]], [[DIC]] | ||
|- | |- | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| Line 119: | Line 119: | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Rheumatology/Immunology/Allergy''' | | '''Rheumatology/Immunology/Allergy''' | ||
| bgcolor="Beige" | Autoimmunity | | bgcolor="Beige" | [[Autoimmunity]] | ||
|- | |- | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| Line 140: | Line 140: | ||
===Causes in alphabetical order=== | ===Causes in alphabetical order=== | ||
* Autoimmunity | * [[Autoimmunity]] | ||
* DIC | * [[DIC]] | ||
* Postpartum hemorrhage | * [[Postpartum hemorrhage]] | ||
* Snake bites | * [[Snake bite|Snake bites]] | ||
* Small and rigid sella | * Small and rigid [[sella]] | ||
* Thrombosis | * [[Thrombosis]] | ||
* Traumatic birth delivery | * Traumatic birth delivery | ||
Revision as of 15:19, 1 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]
Overview
Common causes of Sheehan's syndrome are including massive hemorrhage, hypotension during pregnancy, vascular compression, and vascular occlusion (thrombosis, DIC). Less common causes are including vascular insufficiency due to coronary artery bypass grafting (CABG) in older patients and snake bites (Russell's viper bites).
Causes
Life-threatening Causes
Common Causes
Sheehan's syndrome may be caused by the followings:
- Massive hemorrhage during and after pregnancy
- Vascular compression due to enlarged pituitary gland or small and rigid sella
- Vascular occlusion (thrombosis, DIC)
Less Common Causes
Less common causes of Sheehan's syndrome are including:
- Vascular insufficiency due to CABG in older patients[2]
- Snake bites (Russell's viper bites)[3]
Genetic Causes
- Sheehan's syndrome is not associated with any genetic mutation.
Causes by Organ System
| Cardiovascular | Hypotension, Vascular compression, Hemorrhage |
| Chemical/Poisoning | Snake bites |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | Thrombosis, DIC |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | PPH, Traumatic birth delivery |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | Autoimmunity |
| Sexual | No underlying causes |
| Trauma | Traumatic delivery |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in alphabetical order
- Autoimmunity
- DIC
- Postpartum hemorrhage
- Snake bites
- Small and rigid sella
- Thrombosis
- Traumatic birth delivery
References
- ↑ Matsuzaki S, Endo M, Ueda Y, Mimura K, Kakigano A, Egawa-Takata T, Kumasawa K, Yoshino K, Kimura T (2017). "A case of acute Sheehan's syndrome and literature review: a rare but life-threatening complication of postpartum hemorrhage". BMC Pregnancy Childbirth. 17 (1): 188. doi:10.1186/s12884-017-1380-y. PMC 5471854. PMID 28615049.
- ↑ Davies JS, Scanlon MF (1998). "Hypopituitarism after coronary artery bypass grafting". BMJ. 316 (7132): 682–4. PMC 1112681. PMID 9522796.
- ↑ Antonypillai CN, Wass JA, Warrell DA, Rajaratnam HN (2011). "Hypopituitarism following envenoming by Russell's vipers (Daboia siamensis and D. russelii) resembling Sheehan's syndrome: first case report from Sri Lanka, a review of the literature and recommendations for endocrine management". QJM. 104 (2): 97–108. doi:10.1093/qjmed/hcq214. PMID 21115460.