Toxic Adenoma laboratory findings: Difference between revisions
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Aditya Ganti (talk | contribs) Created page with "__NOTOC__ {{Toxic Adenoma}} {{CMG}} ; {{AE}} {{ADG}} ==Overview== ==Laboratory Findings== ==References== {{reflist|2}}" |
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==Overview== | ==Overview== | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
*Measurement of serum TSH is considered as the initial test in the evaluation of thyroid disorders. | |||
*It should be measured in all patients with a thyroid nodule or goiter. | |||
*The serum free T 4 and free or total T 3 levels are elevated or in the upper part of the normal range. | |||
*Toxic adenomas can be associated with overt or subclinical hyperthyroidism. | |||
**In overt hyperthyroidism, usually both serum (free) T4 and T3 are elevated. | |||
**Isolated T 3 toxicosis, in which the serum T 3 concentration is elevated but free T 4 is normal, occurs in approximately 1% of patients with hyperthyroidism. | |||
*When the TSH is low, but both free T 4 and T 3 levels are normal, the patient has subclinical or mild hyperthyroidism, which is common in toxic multinodular goiter, especially in older patients. | |||
*Findings of routine laboratory tests include: | |||
** elevated serum calcium | |||
** elevated alkaline phosphatase | |||
** elevated ferritin levels | |||
** low (LDL) cholesterol levels. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 15:26, 7 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Laboratory Findings
- Measurement of serum TSH is considered as the initial test in the evaluation of thyroid disorders.
- It should be measured in all patients with a thyroid nodule or goiter.
- The serum free T 4 and free or total T 3 levels are elevated or in the upper part of the normal range.
- Toxic adenomas can be associated with overt or subclinical hyperthyroidism.
- In overt hyperthyroidism, usually both serum (free) T4 and T3 are elevated.
- Isolated T 3 toxicosis, in which the serum T 3 concentration is elevated but free T 4 is normal, occurs in approximately 1% of patients with hyperthyroidism.
- When the TSH is low, but both free T 4 and T 3 levels are normal, the patient has subclinical or mild hyperthyroidism, which is common in toxic multinodular goiter, especially in older patients.
- Findings of routine laboratory tests include:
- elevated serum calcium
- elevated alkaline phosphatase
- elevated ferritin levels
- low (LDL) cholesterol levels.