Celiac disease history and symptoms: Difference between revisions
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Celiac disease can present with classical symptoms such as diarrhea, steatorrhea, weight loss, and growth failure or non-classical symptoms involving outside GI tract. The classic presentation of celiac disease is more common in young children, consisting primarily of gastrointestinal symptoms. In adults, the presentation of celiac disease is often more subtle and can be mistaken for irritable bowel syndrome. Some patients lack any evident gastrointestinal symptoms and instead present with nutritional deficiencies (most commonly iron deficiency) or extra-intestinal symptoms, or are asymptomatic. | Celiac disease can present with classical symptoms such as diarrhea, steatorrhea, weight loss, and growth failure or non-classical symptoms involving outside GI tract. The classic presentation of celiac disease is more common in young children, consisting primarily of gastrointestinal symptoms. In adults, the presentation of celiac disease is often more subtle and can be mistaken for irritable bowel syndrome. Some patients lack any evident gastrointestinal symptoms and instead present with nutritional deficiencies (most commonly iron deficiency) or extra-intestinal symptoms, or are asymptomatic. | ||
'''The following table summarizes the symptoms of celiac disease in adults.'''<ref name="pmid12741468">{{cite journal |vauthors=Zipser RD, Patel S, Yahya KZ, Baisch DW, Monarch E |title=Presentations of adult celiac disease in a nationwide patient support group |journal=Dig. Dis. Sci. |volume=48 |issue=4 |pages=761–4 |year=2003 |pmid=12741468 |doi= |url=}}</ref><ref name="pmid25003268">{{cite journal |vauthors=Lasa JS, Zubiaurre I, Soifer LO |title=Risk of infertility in patients with celiac disease: a meta-analysis of observational studies |journal=Arq Gastroenterol |volume=51 |issue=2 |pages=144–50 |year=2014 |pmid=25003268 |doi= |url=}}</ref><ref name="pmid19018335">{{cite journal |vauthors=Freeman HJ |title=Neurological disorders in adult celiac disease |journal=Can. J. Gastroenterol. |volume=22 |issue=11 |pages=909–11 |year=2008 |pmid=19018335 |pmc=2661192 |doi= |url=}}</ref><ref name="pmid24084055">{{cite journal |vauthors=Wierdsma NJ, van Bokhorst-de van der Schueren MA, Berkenpas M, Mulder CJ, van Bodegraven AA |title=Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients |journal=Nutrients |volume=5 |issue=10 |pages=3975–92 |year=2013 |pmid=24084055 |pmc=3820055 |doi=10.3390/nu5103975 |url=}}</ref> | '''The following table summarizes the symptoms of celiac disease in adults.'''<ref name="pmid12741468">{{cite journal |vauthors=Zipser RD, Patel S, Yahya KZ, Baisch DW, Monarch E |title=Presentations of adult celiac disease in a nationwide patient support group |journal=Dig. Dis. Sci. |volume=48 |issue=4 |pages=761–4 |year=2003 |pmid=12741468 |doi= |url=}}</ref><ref name="pmid25003268">{{cite journal |vauthors=Lasa JS, Zubiaurre I, Soifer LO |title=Risk of infertility in patients with celiac disease: a meta-analysis of observational studies |journal=Arq Gastroenterol |volume=51 |issue=2 |pages=144–50 |year=2014 |pmid=25003268 |doi= |url=}}</ref><ref name="pmid19018335">{{cite journal |vauthors=Freeman HJ |title=Neurological disorders in adult celiac disease |journal=Can. J. Gastroenterol. |volume=22 |issue=11 |pages=909–11 |year=2008 |pmid=19018335 |pmc=2661192 |doi= |url=}}</ref><ref name="pmid24084055">{{cite journal |vauthors=Wierdsma NJ, van Bokhorst-de van der Schueren MA, Berkenpas M, Mulder CJ, van Bodegraven AA |title=Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients |journal=Nutrients |volume=5 |issue=10 |pages=3975–92 |year=2013 |pmid=24084055 |pmc=3820055 |doi=10.3390/nu5103975 |url=}}</ref><ref name="pmid23601438">{{cite journal |vauthors=Casella G, Antonelli E, Di Bella C, Villanacci V, Fanini L, Baldini V, Bassotti G |title=Prevalence and causes of abnormal liver function in patients with coeliac disease |journal=Liver Int. |volume=33 |issue=7 |pages=1128–31 |year=2013 |pmid=23601438 |doi=10.1111/liv.12178 |url=}}</ref> | ||
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Revision as of 19:04, 12 September 2017
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Celiac disease Microchapters |
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Diagnosis |
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Celiac disease history and symptoms On the Web |
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American Roentgen Ray Society Images of Celiac disease history and symptoms |
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Risk calculators and risk factors for Celiac disease history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History
A detailed and thorough history from the patient is necessary. It provides insight into the cause, precipitating factors and associated comorbid conditions. Specific areas of focus when obtaining a history from the patient with celiac disease include:[1]
- Unexplained gastrointestinal symptoms
- Chronic diarrhea
- Symptoms of fatigue and tiredness (iron deficiency anemia)
- Skin rash consistent with dermatitis herpetiformis
- Family history of celiac disease and inflammatory bowel disease
Symptoms
Celiac disease can present with classical symptoms such as diarrhea, steatorrhea, weight loss, and growth failure or non-classical symptoms involving outside GI tract. The classic presentation of celiac disease is more common in young children, consisting primarily of gastrointestinal symptoms. In adults, the presentation of celiac disease is often more subtle and can be mistaken for irritable bowel syndrome. Some patients lack any evident gastrointestinal symptoms and instead present with nutritional deficiencies (most commonly iron deficiency) or extra-intestinal symptoms, or are asymptomatic.
The following table summarizes the symptoms of celiac disease in adults.[2][3][4][5][6]
| Symtpms | ||||||||
|---|---|---|---|---|---|---|---|---|
| Intestinal | Extra-intestinal | |||||||
| Hematologic | Dermatologic | Neurologic | Musculoskeletal | Hepatic | Renal | Cardiac | ||
| Common
Symptoms |
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- | - | - |
| Less common
symptoms |
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References
- ↑ Green PH, Cellier C (2007). "Celiac disease". N. Engl. J. Med. 357 (17): 1731–43. doi:10.1056/NEJMra071600. PMID 17960014.
- ↑ Zipser RD, Patel S, Yahya KZ, Baisch DW, Monarch E (2003). "Presentations of adult celiac disease in a nationwide patient support group". Dig. Dis. Sci. 48 (4): 761–4. PMID 12741468.
- ↑ Lasa JS, Zubiaurre I, Soifer LO (2014). "Risk of infertility in patients with celiac disease: a meta-analysis of observational studies". Arq Gastroenterol. 51 (2): 144–50. PMID 25003268.
- ↑ Freeman HJ (2008). "Neurological disorders in adult celiac disease". Can. J. Gastroenterol. 22 (11): 909–11. PMC 2661192. PMID 19018335.
- ↑ Wierdsma NJ, van Bokhorst-de van der Schueren MA, Berkenpas M, Mulder CJ, van Bodegraven AA (2013). "Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients". Nutrients. 5 (10): 3975–92. doi:10.3390/nu5103975. PMC 3820055. PMID 24084055.
- ↑ Casella G, Antonelli E, Di Bella C, Villanacci V, Fanini L, Baldini V, Bassotti G (2013). "Prevalence and causes of abnormal liver function in patients with coeliac disease". Liver Int. 33 (7): 1128–31. doi:10.1111/liv.12178. PMID 23601438.