Celiac disease causes: Difference between revisions
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==Overview== | ==Overview== | ||
The common causes of celiac disease are autoantibodies to gluten and certain genetic factors. | The common causes of celiac disease are autoantibodies to [[gluten]] and certain [[HLA-DQ|genetic factors]]. | ||
==Causes== | ==Causes== | ||
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Celiac disease is usually caused by: | Celiac disease is usually caused by: | ||
*Autoantibodies against gluten which is found in: | *Autoantibodies against gluten which is found in: | ||
**Wheat | **[[Wheat]] | ||
**Barley | **Barley | ||
**Rye | **Rye | ||
===Genetic Causes=== | ===Genetic Causes=== | ||
*Celiac disease is linked to the HLA genes usually HLA DQ2 and HLA DQ8. | *Celiac disease is linked to the [[HLA]] genes usually [[HLA DQ|HLA DQ2]] and [[HLA DQ|HLA DQ8]]. | ||
** | **CELIAC1 (6p21) | ||
*Non HLA | *Non-HLA genes are also thought to be related to celiac disease: | ||
** | **CELIAC2 (5q31-33) | ||
** | **CELIAC3 (2q33) | ||
** | **CELIAC4 (19p13·1) | ||
==References== | ==References== | ||
Revision as of 20:56, 12 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The common causes of celiac disease are autoantibodies to gluten and certain genetic factors.
Causes
Common Causes
Celiac disease is usually caused by:
- Autoantibodies against gluten which is found in:
- Wheat
- Barley
- Rye
Genetic Causes
- Celiac disease is linked to the HLA genes usually HLA DQ2 and HLA DQ8.
- CELIAC1 (6p21)
- Non-HLA genes are also thought to be related to celiac disease:
- CELIAC2 (5q31-33)
- CELIAC3 (2q33)
- CELIAC4 (19p13·1)