Febrile neutropenia physical examination: Difference between revisions

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Revision as of 17:43, 18 September 2017

Resident
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: F and N; fever and neutropenia; FN; hot and low; hot leuk; neutropenic fever; neutropenic fever syndrome; neutropenic sepsis

Overview

The physical examination should focus on potential sites of infection.[1]

Physical Examination

Skin

Induration and erythema may be minimal. Pustule formation are uncommon in the absence of neutrophils.

Throat

Examination of the oropharynx may reveal ulcers or plaques suggestive of herpes or candidiasis. Mucositis owing to cytotoxic chemotherapy may be indistinguishable from herpetic gingivostomatitis.

Lungs

Auscultation of the lungs may reveal minimal adventitial sounds.

Abdomen

Abdominal pain in neutropenic patients may herald an intraabdominal catastrophe secondary to neutropenic enterocolitis or tumor necrosis.

Other

Examination of catheter sites may disclose erythema, tenderness, or discharge.

References

  1. Freifeld, Alison G. (2011-02-15). "Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 Update by the Infectious Diseases Society of America". Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America. 52 (4): 427–431. doi:10.1093/cid/ciq147. ISSN 1537-6591. PMID 21205990. Unknown parameter |coauthors= ignored (help)