Progressive multifocal leukoencephalopathy history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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History and Symptoms

Symptoms include weakness or paralysis, vision loss, impaired speech, and cognitive deterioration. In addition, the lesions affecting the parietal and occipital lobes can lead to a phenomenon known as Alien hand syndrome.

• Headaches
• Loss of coordination, clumsiness
• Loss of language ability (aphasia)
• Memory loss
• Vision problems
• Weakness of the legs and arms that gets worse

References

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