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Latest revision as of 19:07, 18 September 2017

St. Louis encephalitis Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating St. Louis encephalitis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

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MRI

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Other Imaging Findings

Other Diagnostic Studies

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]; Contributor(s): Vishnu Vardhan Serla M.B.B.S. [3], Irfan Dotani [4]

Overview

The diagnostic method of choice for St. Louis encephalitis is laboratory testing. In St. Louis encephalitis, cerebrospinal fluid examination shows a moderate (typically lymphocytic) pleocytosis. 2/3 of patients with St. Louis encephalitis may have elevated concentration of CSF protein, which usually indicative of neuroinvasive disease. In the absence of a sensitive and non-invasive virus detection method, serologic testing is the primary method for diagnosing St. Louis encephalitis.[1][2]

Laboratory Findings

The diagnostic method of choice for St. Louis encephalitis is laboratory testing. In St. Louis encephalitis, cerebrospinal fluid examination shows a moderate (typically lymphocytic) pleocytosis. 2/3 of patients with St. Louis encephalitis may have elevated concentration of CSF protein, which usually indicative of neuroinvasive disease. In the absence of a sensitive and non-invasive virus detection method, serologic testing is the primary method for diagnosing SLEV infection. A rapid and accurate diagnosis of St. Louis encephalitis can be made by the detection of St. Louis encephalitis-specific IgM antibody in serum or CSF.[1][2]

Other laboratory findings include:

A positive St. Louis encephalitis IgM test result should be confirmed by neutralizing antibody testing of acute- and convalescent-phase serum specimens at the Centers for Disease Control and Prevention.

References

  1. 1.0 1.1 St. Louis Encephalitis Virus Antibodies (IgG, IgM). Quest Diagnostics (2016). http://www.questdiagnostics.com/testcenter/BUOrderInfo.action?tc=34982X&labCode=QTE Accessed on August 1, 2016.
  2. 2.0 2.1 Saint Louis Encephalitis. Centers for Disease Prevention and Control (2009). https://www.cdc.gov/sle/technical/symptoms.html Accessed on August 1, 2016.


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