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'''Protein energy malnutrition complicated by mild dehydration'''
'''Protein energy malnutrition complicated by mild dehydration'''
Most patients with PEM and mild to moderate [[dehydration]] can be treated with [[oral]] or [[Nasogastric intubation|nasogastric administration of fluids.]]  
Most patients with PEM and mild to moderate [[dehydration]] can be treated with [[oral]] or [[Nasogastric intubation|nasogastric administration of fluids.]]  
*The "[[Oral rehydration therapy|oral rehydration salts]]" ([[ORS]]) solution is recommended. It is prepared by dissolving one packet of these special salts in 1 litre of clean drinking-water  
*The "[[Oral rehydration therapy|oral rehydration salts]]" ([[ORS]]) solution is recommended, that is prepared by dissolving one packet of these special salts in 1 litre of clean drinking-water  


'''Protein energy malnutrition complicated by severe dehydration'''
'''Protein energy malnutrition complicated by severe dehydration'''
Patients with severe [[dehydration]] and patients who do not respond after [[oral]] or [[Nasogastric tube|nasogastric fluids]] must be treated by [[Intravenous fluids|intravenous fluid.]]  
Patients with severe [[dehydration]] and patients who do not respond after [[oral]] or [[Nasogastric tube|nasogastric fluids]] must be treated by [[Intravenous fluids|intravenous fluid.]]  
*Compound solution of [[Lactate|sodium lactate]] ([[Lactated Ringer's solution|Ringer's lactate solution]] for [[injection]]; Hartmann's solution)  
*Compound solution of [[Lactate|sodium lactate]] ([[Lactated Ringer's solution|Ringer's lactate solution]] for [[injection]]; Hartmann's solution)  
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'''Treatment of Protein energy malnutrition in the first week'''
'''Treatment of Protein energy malnutrition in the first week'''


The [[malnourished]] child should be fed a dilute [[milk]] feed, such as half-strength [[milk]], for a day or two. When the patient accepts this well, a full-strength [[milk]] feed can be given on days 4 and 5. Towards the end of the week, when feeding is satisfactory, a [[High-energy visible light|high-energy]] milk feed is started.
The [[malnourished]] child should be fed a dilute [[milk]] feed, such as half-strength [[milk]], for a day or two. When the patient accepts this well, a full-strength [[milk]] feed can be given on days 4 and 5. Towards the end of the week, when feeding is satisfactory, a [[High-energy visible light|high-energy]] milk feed is started.
*'''Quantity''': [[Malnourished]] patients should be fed 125 ml/kg body weight each day for the first 4 or 5  days. As the child's [[appetite]] increases on days 6, 7, and 8,oral feeds are increased in amount to 150mllkg body weight per day, and are given every 4  hours (6 feeds per 24 hours).  
*'''Quantity''': [[Malnourished]] patients should be fed 125 ml/kg body weight each day for the first 4 or 5  days. As the child's [[appetite]] increases on days 6, 7, and 8, oral feeds are increased in amount to 150mllkg body weight per day, and are given every 4  hours (6 feeds per 24 hours).  
*'''Frequency''': For the first 2 days [[malnourished]] children should be fed q2h, 12 times daily.  
*'''Frequency''': For the first 2 days [[malnourished]] children should be fed every 2 hours, 12 times daily.  
This [[frequency]] of feeding reduces the risk of the patient developing [[hypothermia]] and [[hypoglycemia]]. Severe [[vomiting]] and [[diarrhea]] are less likely to occur.  When the patient is [[feeding]] satisfactorily, feeds should be given q3hfor the next 2 or 3  days, and then q4hly.
This [[frequency]] of feeding reduces the risk of the patient developing [[hypothermia]] and [[hypoglycemia]]. Severe [[vomiting]] and [[diarrhea]] are less likely to occur.  When the patient is [[feeding]] satisfactorily, feeds should be given every 3 hours, for the next 2 or 3  days, and then every 4 hours..
*'''Type of feed''': Either fluid [[milk]] ([[Cowberry|cow's]], goat's, buffalo's, camel's and canned [[evaporated]] milk) or [[Milk|milk powder]] (skimmed or full-cream powder) can be used to prepare [[milk]] feeds.
*'''Type of feed''': Either fluid [[milk]] ([[Cowberry|cow's]], goat's, buffalo's, camel's and canned [[evaporated]] milk) or [[Milk|milk powder]] (skimmed or full-cream powder) can be used to prepare [[milk]] feeds.
**'''Cow milk''': About 1  liter of full-strength milk feed is prepared by adding 50 g (10 teaspoons) of sugar to 1000 ml undiluted milk.
**'''Cow milk''': About 1  liter of full-strength milk feed is prepared by adding 50 g (10 teaspoons) of sugar to 1000 ml undiluted milk.
**'''[[Evaporated|Evaporated milk]]''': 500 ml of [[Evaporated|evaporated milk i]]<nowiki/>s mixed with 500 ml of water and 50 g of [[sugar]] added to prepare about 1 liter of full-strength milk.   
**'''[[Evaporated|Evaporated milk]]''': 500 ml of [[Evaporated|evaporated milk i]]<nowiki/>s mixed with 500 ml of water and 50 g of [[sugar]] added to prepare about 1 liter of full-strength milk.   
**'''Full-cream milk powder''': Add 150 g of milk powder -  i.e., 30 teaspoons or 30 level scoops (as supplied with the tin)-and 50 g of sugar to 1000 ml of water to prepare approximately 1 liter of full-strength milk.  
**'''Full-cream milk powder''': Add 150 g of milk powder -  i.e., 30 teaspoons or 30 level scoops (as supplied with the tin)-and 50 g of sugar to 1000 ml of water to prepare approximately 1 liter of full-strength milk.  
**'''Skimmed milk powder''': Mix 75 g (15 teaspoons) of skimmed milk powder with 30 g (35 ml) of vegetable oil(6 teaspoons) and 50 g of sugar (10 teaspoons) to a smooth paste. Gradually add: Mix 50 g 00 teaspoons) of sugar into 1000 ml of yogurt to make approximately 1 litre of full-strength feed.  
**'''Skimmed milk powder''': Mix 75 g (15 teaspoons) of skimmed milk powder with 30 g (35 ml) of vegetable oil (6 teaspoons) and 50 g of sugar (10 teaspoons) to a smooth paste. Gradually add: Mix 50 g 00 teaspoons) of sugar into 1000 ml of yogurt to make approximately 1 litre of full-strength feed.  
'''Mineral and vitamin supplements'''
'''Mineral and vitamin supplements'''
*[[Potassium]] supplements
*[[Potassium]] supplements

Revision as of 20:36, 19 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2]

Overview

In some cases, protein energy malnutrition may be complicated by dehydration and specific infections such as pneumonia and septicemia. In such cases, protein energy malnutrition is a medical emergency and requires prompt treatment with oral rehydration and antibiotics.

Medical therapy

In some cases, protein energy malnutrition may be complicated by dehydration and specific infections, such as pneumonia and septicemia. In such cases, protein energy malnutrition is a medical emergency and requires prompt treatment with antibiotics.[1]

Protein energy malnutrition complicated by mild dehydration

Most patients with PEM and mild to moderate dehydration can be treated with oral or nasogastric administration of fluids.

  • The "oral rehydration salts" (ORS) solution is recommended, that is prepared by dissolving one packet of these special salts in 1 litre of clean drinking-water

Protein energy malnutrition complicated by severe dehydration

Patients with severe dehydration and patients who do not respond after oral or nasogastric fluids must be treated by intravenous fluid.

Protein energy malnutrition complicated by infections

  • Infants 6 months to 1 year
    • Preferred regimen (1): Procaine benzyl-penicillin (water-miscible)IM (1-2 ml q1d for 5-10 days)
    • Preferred regimen (2): Ampicillin 125 mg at q6h intervals for 5-10 days (maximum, 500 mg per dose)
    • Alternative regimen (1): Chloramphenicol 50 mg/kg body weight q24h 6-hour intervals for 5days (maximum, 500 mg per day)
    • Alternative regimen (2): Tetracycline 5-50 mg/kg body weight orally q24h at 6-hour intervals for 5 days, or 10-15 mg/kg body weight intravenously q24h at 12hour intervals for 5 days

Treatment of Protein energy malnutrition in the first week

The malnourished child should be fed a dilute milk feed, such as half-strength milk, for a day or two. When the patient accepts this well, a full-strength milk feed can be given on days 4 and 5. Towards the end of the week, when feeding is satisfactory, a high-energy milk feed is started.

  • Quantity: Malnourished patients should be fed 125 ml/kg body weight each day for the first 4 or 5 days. As the child's appetite increases on days 6, 7, and 8, oral feeds are increased in amount to 150mllkg body weight per day, and are given every 4 hours (6 feeds per 24 hours).
  • Frequency: For the first 2 days malnourished children should be fed every 2 hours, 12 times daily.

This frequency of feeding reduces the risk of the patient developing hypothermia and hypoglycemia. Severe vomiting and diarrhea are less likely to occur. When the patient is feeding satisfactorily, feeds should be given every 3 hours, for the next 2 or 3 days, and then every 4 hours..

  • Type of feed: Either fluid milk (cow's, goat's, buffalo's, camel's and canned evaporated milk) or milk powder (skimmed or full-cream powder) can be used to prepare milk feeds.
    • Cow milk: About 1 liter of full-strength milk feed is prepared by adding 50 g (10 teaspoons) of sugar to 1000 ml undiluted milk.
    • Evaporated milk: 500 ml of evaporated milk is mixed with 500 ml of water and 50 g of sugar added to prepare about 1 liter of full-strength milk.
    • Full-cream milk powder: Add 150 g of milk powder - i.e., 30 teaspoons or 30 level scoops (as supplied with the tin)-and 50 g of sugar to 1000 ml of water to prepare approximately 1 liter of full-strength milk.
    • Skimmed milk powder: Mix 75 g (15 teaspoons) of skimmed milk powder with 30 g (35 ml) of vegetable oil (6 teaspoons) and 50 g of sugar (10 teaspoons) to a smooth paste. Gradually add: Mix 50 g 00 teaspoons) of sugar into 1000 ml of yogurt to make approximately 1 litre of full-strength feed.

Mineral and vitamin supplements

References

  1. Spady DW, Payne PR, Picou D, Waterlow JC (1976). "Energy balance during recovery from malnutrition". Am J Clin Nutr. 29 (10): 1073–88. PMID 823814.