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==Risk factors==
Common risk factors that can trigger myxedema coma in patients with hypothyroidism include:
• Hypothermia
• CVA
• CHF
• Infections ( pneumonia, influenza, UTI, sepsis)
• Drugs ( Anesthestics, narcotics, amidirone, Lithium carbonate) 6486153
• GI bleeding
• Metabolic disturbances(Hypoglycemia, hyponatremia, acidosis, hypercalcemia, hypoxemia, hypercapneia)
==History==


* History of antecedent thyroid disease
* History of radioiodine therapy or thyroidectomy
* Discontinuation of medications.
==Historical Perspective==
*In 874, Gull was the first physician to describe hypothyroidism under the name myxedema due to its characteristics of swollen skin and its mucin content.
*In 1883, Semon was the first to establish a relationship between patients undergoing thyroidectomy and later developing symptoms of myxedema.
*In 1888, Clinical Society of London presented a paper describing that extreme loss of thyroid harmone can lead to cretinism and myxedema.
*In 1891, Murray was the first physician to discover cure for myxedema by using hypodermic injections of sheep thyroid extract.

Revision as of 22:14, 19 September 2017

Risk factors

Common risk factors that can trigger myxedema coma in patients with hypothyroidism include: • Hypothermia • CVA • CHF • Infections ( pneumonia, influenza, UTI, sepsis) • Drugs ( Anesthestics, narcotics, amidirone, Lithium carbonate) 6486153 • GI bleeding • Metabolic disturbances(Hypoglycemia, hyponatremia, acidosis, hypercalcemia, hypoxemia, hypercapneia)

History

  • History of antecedent thyroid disease
  • History of radioiodine therapy or thyroidectomy
  • Discontinuation of medications.

Historical Perspective

  • In 874, Gull was the first physician to describe hypothyroidism under the name myxedema due to its characteristics of swollen skin and its mucin content.
  • In 1883, Semon was the first to establish a relationship between patients undergoing thyroidectomy and later developing symptoms of myxedema.
  • In 1888, Clinical Society of London presented a paper describing that extreme loss of thyroid harmone can lead to cretinism and myxedema.
  • In 1891, Murray was the first physician to discover cure for myxedema by using hypodermic injections of sheep thyroid extract.