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{{CMG}};{{AE}}{{DAMI}}
{{CMG}};{{AE}}{{DAMI}}
==Overview==
==Overview==
Kwashiorkor is a form of [[malnutrition]] that occurs when there is not enough protein in the diet.
Marasmus is a form of [[malnutrition]] that results when [[subcutaneous fat]] and [[muscle]] are lost because of mobilization of all available [[energy]] and [[nutrients]]. Deficiency of [[protein]] as well as [[energy]] [[nutrients]] (that is [[carbohydrates]] and [[fats]]) in the [[diet]] may lead to marasmus. Marasmus typically occurs in children below the age of 1 year.


==Causes==
==Causes==
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*Limited food supply
*Limited food supply
*Low levels of education (when people do not understand how to eat a proper diet)  
*Low levels of education (when people do not understand how to eat a proper diet)  
This disease is more common in very poor countries. It often occurs during a drought or other natural disaster, or during political unrest. These conditions are responsible for a lack of food, which leads to malnutrition.
This disease is more common in very poor countries. It often occurs during a drought or other natural disaster, or during political unrest. These conditions are responsible for a lack of food, which leads to malnutrition. Marasmus is very rare in children in the United States. There are only isolated cases. However, one government estimate suggests that as many as 50% of elderly people in nursing homes in the United States do not get enough protein in their diet. When marasmus does occur in the United States, it is most often a sign of child abuse and severe neglect.
 
[[Kwashiorkor]] is very rare in children in the United States. There are only isolated cases. However, one government estimate suggests that as many as 50% of elderly people in nursing homes in the United States do not get enough protein in their diet.
 
When kwashiorkor does occur in the United States, it is most often a sign of child abuse and severe neglect.


==Symptoms==
==Symptoms==
Symptoms include:
Symptoms include:
*Changes in skin [[pigmentation]]
* Patient appears like an 'elderly man'
 
*[[Xerostomia|Dry]] and flaking/peeling [[skin]] but no changes in [[color]]
*[[Muscle mass|Loss of muscle mass]]
*[[Muscle mass|Loss of muscle mass]]
*Sunken [[eyes]]
*Protruded [[cheeks]]
*Loss of fullness near the mouth area giving rise to 'monkey-like' facies
*Swelling of body ([[edema]]) is generally not seen in marasmus
*Sunken belly
*[[Diarrhea]]
*[[Diarrhea]]
*Failure to gain weight and grow
*Failure to gain weight and grow
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*Increased and more severe infections due to damaged [[Immune systems|immune system]]
*Increased and more severe infections due to damaged [[Immune systems|immune system]]
*[[Irritability]]
*[[Irritability]]
*Large belly that sticks out (protrudes)
*[[Lethargy]] or [[apathy]]
*[[Lethargy]] or [[apathy]]
*[[Rash]] ([[dermatitis]])
*[[Rash]] ([[dermatitis]])
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==Diagnosis==
==Diagnosis==
The physical exam may show an enlarged liver (hepatomegaly) and general swelling.
The physical exam may show an enlarged liver (hepatomegaly) and general swelling. Tests may include:
Tests may include:
*[[Arterial blood gas]]
*[[Arterial blood gas]]
*[[BUN]]
*[[BUN]]
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==Treatment==
==Treatment==
Getting more [[calories]] and [[protein]] will correct kwashiorkor, if treatment is started early enough. However, children who have had this condition will never reach their full potential for [[height]] and [[growth]].
Getting more [[calories]] and [[protein]] will correct marasmus, if treatment is started early enough. However, children who have had this condition will never reach their full potential for [[height]] and [[growth]].


Treatment depends on the severity of the condition. People who are in [[shock]] need treatment right away to restore blood volume and maintain blood pressure.
Treatment depends on the severity of the condition. People who are in [[shock]] need treatment right away to restore blood volume and maintain [[blood pressure]]. [[Calories]] are given first in the form of [[carbohydrates]], simple sugars, and [[fats]]. Proteins are started after other sources of [[calories]] have already provided energy. [[Vitamin]] and [[mineral]] supplements are essential.
Calories are given first in the form of carbohydrates, simple sugars, and fats. Proteins are started after other sources of calories have already provided energy. Vitamin and mineral supplements are essential.


Since the person will have been without much food for a long period of time, eating can cause problems, especially if the calories are too high at first. Food must be reintroduced slowly.
Since the person will have been without much food for a long period of time, eating can cause problems, especially if the [[calories]] are too high at first. Food must be reintroduced slowly.


Many malnourished children will develop intolerance to milk sugar (lactose intolerance). They will need to be given supplements with the enzyme lactase so that they can tolerate milk products.
Many malnourished children will develop intolerance to milk sugar (lactose intolerance). They will need to be given supplements with the [[enzyme]] [[lactase]] so that they can tolerate milk products.


==Outlook (Prognosis)==
==Outlook (Prognosis)==
Getting treatment early generally leads to good results. Treating kwashiorkor in its late stages will improve the child's general health. However, the child may be left with permanent physical and mental problems. If treatment is not given or comes too late, this condition is life threatening.
Getting treatment early generally leads to good results. Treating marasmus in its late stages will improve the child's general health. However, the child may be left with permanent physical and mental problems. If treatment is not given or comes too late, this condition is life threatening.
Possible Complications


==Complications==
==Complications==
Complications may include:
Complications may include:
*Coma
*[[Coma]]
*Permanent mental and physical disability
*Permanent [[mental]] and physical disability
*Shock
*[[Shock]]


==When to Contact a Medical Professional==
==When to Contact a Medical Professional==
Call your health care provider if your child has symptoms of kwashiorkor.
Call your health care provider if your child has symptoms of marasmus.


==Prevention==
==Prevention==
To prevent kwashiorkor, make sure the diet has enough carbohydrates, fat (at least 10% of total calories), and protein (12% of total calories).
To prevent marasmus, make sure the diet has enough [[carbohydrates]], [[fat]] (at least 10% of total [[Calorie|calories]]), and [[protein]] (12% of total [[calories]]).


==Alternative Names==
==Alternative Names==


Protein malnutrition; Protein-calorie malnutrition; Malignant malnutrition
Protein malnutrition; Protein-calorie malnutrition; Malignant malnutrition

Revision as of 16:03, 20 September 2017


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Protein energy malnutrition

Overview

Causes

Symptoms

Diagnosis

Treatment options

Possible complications

When to contact a medical professional

Prevention

Alternative names

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2]

Overview

Marasmus is a form of malnutrition that results when subcutaneous fat and muscle are lost because of mobilization of all available energy and nutrients. Deficiency of protein as well as energy nutrients (that is carbohydrates and fats) in the diet may lead to marasmus. Marasmus typically occurs in children below the age of 1 year.

Causes

Kwashiorkor is most common in areas where there is:

  • Famine
  • Limited food supply
  • Low levels of education (when people do not understand how to eat a proper diet)

This disease is more common in very poor countries. It often occurs during a drought or other natural disaster, or during political unrest. These conditions are responsible for a lack of food, which leads to malnutrition. Marasmus is very rare in children in the United States. There are only isolated cases. However, one government estimate suggests that as many as 50% of elderly people in nursing homes in the United States do not get enough protein in their diet. When marasmus does occur in the United States, it is most often a sign of child abuse and severe neglect.

Symptoms

Symptoms include:

  • Patient appears like an 'elderly man'

Diagnosis

The physical exam may show an enlarged liver (hepatomegaly) and general swelling. Tests may include:

Treatment

Getting more calories and protein will correct marasmus, if treatment is started early enough. However, children who have had this condition will never reach their full potential for height and growth.

Treatment depends on the severity of the condition. People who are in shock need treatment right away to restore blood volume and maintain blood pressure. Calories are given first in the form of carbohydrates, simple sugars, and fats. Proteins are started after other sources of calories have already provided energy. Vitamin and mineral supplements are essential.

Since the person will have been without much food for a long period of time, eating can cause problems, especially if the calories are too high at first. Food must be reintroduced slowly.

Many malnourished children will develop intolerance to milk sugar (lactose intolerance). They will need to be given supplements with the enzyme lactase so that they can tolerate milk products.

Outlook (Prognosis)

Getting treatment early generally leads to good results. Treating marasmus in its late stages will improve the child's general health. However, the child may be left with permanent physical and mental problems. If treatment is not given or comes too late, this condition is life threatening.

Complications

Complications may include:

When to Contact a Medical Professional

Call your health care provider if your child has symptoms of marasmus.

Prevention

To prevent marasmus, make sure the diet has enough carbohydrates, fat (at least 10% of total calories), and protein (12% of total calories).

Alternative Names

Protein malnutrition; Protein-calorie malnutrition; Malignant malnutrition